Interactor 1: CASR (P41180)
Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1)
Gene: CASR

Interactor 2: CASR (P41180)
Extracellular calcium-sensing receptor (CaR) (CaSR) (hCasR) (Parathyroid cell calcium-sensing receptor 1) (PCaR1)
Gene: CASR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.865

The method score is based on:

Property Details
Experiments 15239670, 9722601, 34194040
Identification Methods pull down, x-ray crystallography, electron microscopy 3D single particle reconstruction, molecular sieving
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_3~7tm_3, 7tm_3~NCD3G, ANF_receptor~ANF_receptor, ANF_receptor~NCD3G, NCD3G~NCD3G
Common GO terms GO:0001503 - ossification
GO:0002931 - response to ischemia
GO:0004435 - phosphatidylinositol phospholipase C activity
GO:0004930 - G protein-coupled receptor activity
GO:0005178 - integrin binding
and 40 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1078
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024