HitPredict

Interactor 1: SYIC (P41252)
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
Gene: IARS1

Interactor 2: FOXL2 (P58012)
Forkhead box protein L2
Gene: FOXL2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1262 Hs			1 376
+	Hs
		783024 SYIC_HUMAN (1-1262): 0: 1480: 100.00		FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21
+	Hs
		783098 SYIC_HUMAN (1-1262): 0: 1480: 100.00		FOXB1_HUMAN (43-352): 7.6e-43: 153: 27.01
+	Hs
		783061 SYIC_HUMAN (1-1262): 0: 1480: 100.00		FOXI2_HUMAN (54-143): 5.64e-24: 102: 65.56
+	Hs
		643833 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXL2_HUMAN (1-376): 1.34e-71: 230: 100.00
+	Hs
		643830 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXG1_HUMAN (11-334): 5.9e-50: 176: 27.80
+	Hs
		643831 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXA1_HUMAN (10-340): 9.06e-47: 167: 26.55
+	Hs
		643854 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXL1_HUMAN (28-215): 7.39e-48: 167: 45.21
+	Hs
		643852 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXC1_HUMAN (14-227): 2.8e-43: 159: 36.70
+	Hs
		643853 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXI1_HUMAN (6-288): 2.01e-43: 156: 33.57
+	Hs
		643902 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXB1_HUMAN (43-352): 7.6e-43: 153: 27.01
+	Hs
		643882 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXI2_HUMAN (54-143): 5.64e-24: 102: 65.56
+	Hs
		126431 SYVC_HUMAN (1-961): 0: 823: 19.24		FOXE1_HUMAN (54-142): 1.43e-21: 96.7: 67.42
+	Hs
		208947 SYIM_HUMAN (3-903): 0: 698: 25.13		FOXS1_HUMAN (43-324): 1.74e-44: 158: 34.50
+	Hs
		1306875 SYLC_HUMAN (3-993): 0: 668: 16.08		FOXB1_HUMAN (43-352): 7.6e-43: 153: 27.01