Protein: BPTF
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)

Gene: BPTF
Organism: Homo sapiens
Interactions: 155
UniProt ID: Q12830

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001892 - embryonic placenta development
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

997694

RBBP4
Histone-binding protein RBBP4

6

20

Small-scale

0.738

High

1017306

RBBP7
Histone-binding protein RBBP7

5

20

Small-scale

0.718

High

1017321

BAP18
Chromatin complexes subunit BAP18

5

5

High-throughput

0.709

High

658659

SMCA1
Probable global transcription activator SNF2L1

4

20

Small-scale

0.699

High

316024

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.691

High

934702

H31
Histone H3.1

4

20

Small-scale

0.676

High

1017300

BRD3
Bromodomain-containing protein 3

1

19

High-throughput

0.665

High

952300

H33
Histone H3.3

3

20

Small-scale

0.660

High

229378

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

3

20

Small-scale

0.656

High

917179

H4
Histone H4

2

20

Small-scale

0.654

High

1017345

DPY30
Protein dpy-30 homolog

3

3

Small-scale

0.651

High

149853

RFXK
DNA-binding protein RFXANK

2

20

High-throughput

0.628

High

1017362

HSPB7
Heat shock protein beta-7

2

11

High-throughput

0.628

High

197976

PHF1
PHD finger protein 1

1

11

High-throughput

0.618

High

244354

BRD4
Bromodomain-containing protein 4

1

19

High-throughput

0.618

High

296001

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.618

High

631413

BRD2
Bromodomain-containing protein 2

1

17

High-throughput

0.618

High

879233

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

20

High-throughput

0.618

High

1017286

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.618

High

1017290

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.618

High

1017295

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.618

High

1017327

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

20

High-throughput

0.618

High

1017339

PHF12
PHD finger protein 12

1

18

High-throughput

0.618

High

1017343

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.618

High

1017367

TRI33
E3 ubiquitin-protein ligase TRIM33

1

19

High-throughput

0.618

High

1017368

MTF2
Metal-response element-binding transcription factor 2

1

11

High-throughput

0.618

High

211007

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

2

14

High-throughput

0.611

High

470008

H2AZ
Histone H2A.Z

2

20

High-throughput

0.611

High

880246

MAZ
Myc-associated zinc finger protein

2

19

Small-scale

0.609

High

268052

EED
Polycomb protein EED

2

20

High-throughput

0.584

High

607815

USF1
Upstream stimulatory factor 1

2

20

Small-scale

0.584

High

1017299

SUZ12
Polycomb protein SUZ12

2

6

High-throughput

0.584

High

1017304

EZH2
Histone-lysine N-methyltransferase EZH2

2

20

High-throughput

0.584

High

1017307

H31T
Histone H3.1t

2

20

Small-scale

0.571

High

346644

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.571

High

323717

BAG2
BAG family molecular chaperone regulator 2

1

10

High-throughput

0.536

High

455371

PARP1
Poly [ADP-ribose] polymerase 1

1

20

High-throughput

0.536

High

739092

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

7

High-throughput

0.536

High

795741

MAGA3
Melanoma-associated antigen 3

1

15

High-throughput

0.536

High

853579

IMA5
Importin subunit alpha-5

1

20

High-throughput

0.536

High

964171

FOXK2
Forkhead box protein K2

1

20

High-throughput

0.536

High

1017289

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

5

High-throughput

0.536

High

1017294

SMC1A
Structural maintenance of chromosomes protein 1A

1

20

High-throughput

0.536

High

1017308

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1017314

L2GL2
LLGL scribble cell polarity complex component 2

1

14

High-throughput

0.536

High

1017323

K2C78
Keratin, type II cytoskeletal 78

1

15

High-throughput

0.536

High

1017324

ZN784
Zinc finger protein 784

1

15

High-throughput

0.536

High

1017366

TPX2
Targeting protein for Xklp2

1

6

High-throughput

0.536

High

1017316

H32
Histone H3.2

1

20

Small-scale

0.527

High

1017293

KEAP1
Kelch-like ECH-associated protein 1

1

6

Small-scale

0.527

High

914942

RS4X
Small ribosomal subunit protein eS4, X isoform

1

4

High-throughput

0.515

High

1017333

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

352965

IL1A
Interleukin-1 alpha

1

0

High-throughput

0.513

High

1017313

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

1017291

SQSTM
Sequestosome-1

1

5

High-throughput

0.508

High

902552

SUMO2
Small ubiquitin-related modifier 2

1

15

High-throughput

0.501

High

950158

SMAD3
Mothers against decapentaplegic homolog 3

1

20

Small-scale

0.501

High

1017303

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.501

High

1017305

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.501

High

1017350

N62CL
Nucleoporin-62 C-terminal-like protein

1

5

High-throughput

0.489

High

1017369

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

1

High-throughput

0.489

High

63970

DUXA
Double homeobox protein A

1

20

High-throughput

0.479

High

146811

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

7

High-throughput

0.479

High

148737

CTRO
Citron Rho-interacting kinase

1

17

High-throughput

0.479

High

158778

HAT1
Histone acetyltransferase type B catalytic subunit

1

4

High-throughput

0.479

High

179619

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

20

High-throughput

0.479

High

257773

SIN3B
Paired amphipathic helix protein Sin3b

1

8

High-throughput

0.479

High

260859

H2AY
Core histone macro-H2A.1

1

20

High-throughput

0.479

High

265194

SAP30
Histone deacetylase complex subunit SAP30

1

5

High-throughput

0.479

High

316868

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

328539

MBD3
Methyl-CpG-binding domain protein 3

1

16

High-throughput

0.479

High

338344

EGFR
Epidermal growth factor receptor

1

14

High-throughput

0.479

High

386625

P53
Cellular tumor antigen p53

1

20

High-throughput

0.479

High

414497

PRGR
Progesterone receptor

1

20

Small-scale

0.479

High

486901

MYBB
Myb-related protein B

1

17

High-throughput

0.479

High

523701

XRCC6
X-ray repair cross-complementing protein 6

1

20

High-throughput

0.479

High

542009

ETS1
Protein C-ets-1

1

20

High-throughput

0.479

High

545968

MYOD1
Myoblast determination protein 1

1

20

High-throughput

0.479

High

552592

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

555434

H2AX
Histone H2AX

1

20

High-throughput

0.479

High

569657

CEBPB
CCAAT/enhancer-binding protein beta

1

20

High-throughput

0.479

High

632711

TYY1
Transcriptional repressor protein YY1

1

20

High-throughput

0.479

High

641391

PAX6
Paired box protein Pax-6

1

18

High-throughput

0.479

High

651064

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

9

High-throughput

0.479

High

652831

APEX1
DNA repair nuclease/redox regulator APEX1

1

7

High-throughput

0.479

High

658491

TEAD1
Transcriptional enhancer factor TEF-1

1

3

High-throughput

0.479

High

692128

ELF1
ETS-related transcription factor Elf-1

1

20

High-throughput

0.479

High

720331

RFA3
Replication protein A 14 kDa subunit

1

7

High-throughput

0.479

High

727513

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

749430

BRCA1
Breast cancer type 1 susceptibility protein

1

14

High-throughput

0.479

High

782532

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

798876

GATA4
Transcription factor GATA-4

1

20

High-throughput

0.479

High

808555

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

817983

SOX2
Transcription factor SOX-2

1

20

Small-scale

0.479

High

828212

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

831270

CEBPA
CCAAT/enhancer-binding protein alpha

1

20

High-throughput

0.479

High

884142

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

918323

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

944757

RED1
Double-stranded RNA-specific editase 1

1

19

High-throughput

0.479

High

967857

PO5F1
POU domain, class 5, transcription factor 1

1

20

High-throughput

0.479

High

971780

HEN1
Helix-loop-helix protein 1

1

20

High-throughput

0.479

High

990028

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

4

High-throughput

0.479

High

1017287

CAF1A
Chromatin assembly factor 1 subunit A

1

13

High-throughput

0.479

High

1017288

CAF1B
Chromatin assembly factor 1 subunit B

1

20

High-throughput

0.479

High

1017292

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.479

High

1017296

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1017297

CUL7
Cullin-7

1

10

High-throughput

0.479

High

1017298

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.479

High

1017301

PDIA6
Protein disulfide-isomerase A6

1

16

High-throughput

0.479

High

1017302

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.479

High

1017309

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

1017310

LIN52
Protein lin-52 homolog

1

1

High-throughput

0.479

High

1017311

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

10

High-throughput

0.479

High

1017312

LIN9
Protein lin-9 homolog

1

3

High-throughput

0.479

High

1017315

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1017317

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

17

High-throughput

0.479

High

1017318

SLN11
Schlafen family member 11

1

5

High-throughput

0.479

High

1017319

TAXB1
Tax1-binding protein 1

1

20

High-throughput

0.479

High

1017320

P66A
Transcriptional repressor p66-alpha

1

18

High-throughput

0.479

High

1017322

SMC5
Structural maintenance of chromosomes protein 5

1

20

High-throughput

0.479

High

1017325

HJURP
Holliday junction recognition protein

1

1

High-throughput

0.479

High

1017326

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1017328

ZN296
Zinc finger protein 296

1

20

High-throughput

0.479

High

1017329

GATD1
GATA zinc finger domain-containing protein 1

1

2

High-throughput

0.479

High

1017330

P66B
Transcriptional repressor p66-beta

1

18

High-throughput

0.479

High

1017331

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1017332

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.479

High

1017336

LIN37
Protein lin-37 homolog

1

1

High-throughput

0.479

High

1017337

Z512B
Zinc finger protein 512B

1

20

High-throughput

0.479

High

1017338

PWP2A
PWWP domain-containing protein 2A

1

18

High-throughput

0.479

High

1017340

SIN3A
Paired amphipathic helix protein Sin3a

1

8

High-throughput

0.479

High

1017341

TBX5
T-box transcription factor TBX5

1

20

High-throughput

0.479

High

1017342

ELF4
ETS-related transcription factor Elf-4

1

20

High-throughput

0.479

High

1017344

NSD3
Histone-lysine N-methyltransferase NSD3

1

20

Small-scale

0.479

High

1017346

BC11B
B-cell lymphoma/leukemia 11B

1

19

High-throughput

0.479

High

1017347

WWTR1
WW domain-containing transcription regulator protein 1

1

20

High-throughput

0.479

High

1017348

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

1017349

BC11A
B-cell lymphoma/leukemia 11A

1

17

High-throughput

0.479

High

1017351

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

1017352

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

10

High-throughput

0.479

High

1017354

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

20

High-throughput

0.479

High

1017355

RAD18
E3 ubiquitin-protein ligase RAD18

1

5

High-throughput

0.479

High

1017356

DCA13
DDB1- and CUL4-associated factor 13

1

20

Small-scale

0.479

High

1017357

AKIP
Small ribosomal subunit protein mS38

1

2

High-throughput

0.479

High

1017359

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

10

High-throughput

0.479

High

1017360

ZN219
Zinc finger protein 219

1

16

High-throughput

0.479

High

1017361

MBD2
Methyl-CpG-binding domain protein 2

1

16

High-throughput

0.479

High

1017363

ZRAN1
Ubiquitin thioesterase ZRANB1

1

19

High-throughput

0.479

High

1017364

HMGX4
HMG domain-containing protein 4

1

20

High-throughput

0.479

High

1017365

HECD1
E3 ubiquitin-protein ligase HECTD1

1

20

High-throughput

0.479

High

1017353

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.458

High

108894

H0YIS7
RNASEK-C17orf49 readthrough

1

5

High-throughput

0.445

High

1017358

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.437

High

1017334

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1017335

CC049
Putative uncharacterized protein C3orf49

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024