Protein: NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6)

Gene: NR3L1, NCR3LG1
Organism: Homo sapiens
Interactions: 86
UniProt ID: Q68D85

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0048018 - receptor ligand activity
GO:0051132 - NK T cell activation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168416

NCTR3
Natural cytotoxicity triggering receptor 3

6

0

Small-scale

0.908

High

1228639

RAE1E
Retinoic acid early transcript 1E

2

20

High-throughput

0.811

High

627535

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

2

20

High-throughput

0.789

High

1186206

CEA21
Cell adhesion molecule CEACAM21

2

11

High-throughput

0.705

High

761244

RYK
Tyrosine-protein kinase RYK

4

20

Small-scale

0.696

High

880152

PTH2R
Parathyroid hormone 2 receptor

1

4

High-throughput

0.691

High

1228648

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

12

High-throughput

0.691

High

1228632

TM11B
Transmembrane protease serine 11B

1

13

High-throughput

0.665

High

648555

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.646

High

1055059

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

20

High-throughput

0.646

High

141933

PODXL
Podocalyxin

2

2

High-throughput

0.628

High

846758

GRK6
G protein-coupled receptor kinase 6

2

4

High-throughput

0.628

High

898089

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

2

2

High-throughput

0.628

High

1047224

ATP7A
Copper-transporting ATPase 1

2

8

High-throughput

0.628

High

1228638

DGLB
Diacylglycerol lipase-beta

2

1

High-throughput

0.628

High

1228646

XPO6
Exportin-6

2

2

High-throughput

0.628

High

1228647

MYADM
Myeloid-associated differentiation marker

2

1

High-throughput

0.628

High

363414

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.618

High

410899

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.618

High

774413

BASI
Basigin

1

13

High-throughput

0.618

High

787180

BMR1A
Bone morphogenetic protein receptor type-1A

1

4

High-throughput

0.618

High

1177222

MICA
MHC class I polypeptide-related sequence A

1

20

High-throughput

0.618

High

1228627

I20RB
Interleukin-20 receptor subunit beta

1

1

High-throughput

0.618

High

1228656

TMPS4
Transmembrane protease serine 4

1

14

High-throughput

0.618

High

378118

TNFA
Tumor necrosis factor

2

1

High-throughput

0.611

High

1203684

TTMP
TPA-induced transmembrane protein

2

2

High-throughput

0.606

High

1228634

PLPP6
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6

2

2

High-throughput

0.606

High

178633

DEGS1
Sphingolipid delta(4)-desaturase DES1

2

0

High-throughput

0.602

High

190389

COPT1
High affinity copper uptake protein 1

2

0

High-throughput

0.602

High

1228636

MIGA1
Mitoguardin 1

2

0

High-throughput

0.602

High

540500

LAMP1
Lysosome-associated membrane glycoprotein 1

2

4

High-throughput

0.588

High

1228635

NRAC
Nutritionally-regulated adipose and cardiac enriched protein homolog

2

0

High-throughput

0.580

High

1228660

STX8
Syntaxin-8

2

0

High-throughput

0.580

High

1228630

MILR1
Allergin-1

1

13

High-throughput

0.575

High

71336

F1712
Protein FAM171A2

2

2

High-throughput

0.574

High

354348

TOM40
Mitochondrial import receptor subunit TOM40 homolog

2

1

High-throughput

0.574

High

783104

ARL2
ADP-ribosylation factor-like protein 2

2

11

High-throughput

0.574

High

1109458

ATR
Serine/threonine-protein kinase ATR

2

7

High-throughput

0.574

High

1228629

MMS22
Protein MMS22-like

2

1

High-throughput

0.574

High

1228653

XPO5
Exportin-5

2

10

High-throughput

0.574

High

720569

TSPO
Translocator protein

2

1

High-throughput

0.553

High

1228658

TM14C
Transmembrane protein 14C

2

1

High-throughput

0.553

High

139234

UPK2
Uroplakin-2

1

1

High-throughput

0.536

High

689948

IL3RA
Interleukin-3 receptor subunit alpha

1

10

High-throughput

0.536

High

722489

CTR1
High affinity cationic amino acid transporter 1

1

8

High-throughput

0.536

High

834670

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

1

High-throughput

0.536

High

1228649

PD1L2
Programmed cell death 1 ligand 2

1

17

High-throughput

0.536

High

692999

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.515

High

1228645

MYCT
Proton myo-inositol cotransporter

1

0

High-throughput

0.513

High

887550

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.489

High

1228628

DUSTY
Dual serine/threonine and tyrosine protein kinase

1

1

High-throughput

0.489

High

1228657

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

4

High-throughput

0.489

High

125496

LEG9
Galectin-9

1

15

High-throughput

0.479

High

376510

LDLR
Low-density lipoprotein receptor

1

3

High-throughput

0.479

High

472079

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.479

High

1228640

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

1

High-throughput

0.479

High

256054

S19A2
Thiamine transporter 1

1

3

High-throughput

0.445

High

614696

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

7

High-throughput

0.445

High

1228641

MOT10
Monocarboxylate transporter 10

1

5

High-throughput

0.445

High

127351

LEG8
Galectin-8

1

15

High-throughput

0.437

High

164586

TNPO2
Transportin-2

1

10

High-throughput

0.437

High

293838

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

1228655

S40A1
Ferroportin

1

0

High-throughput

0.426

High

1131549

MFS10
Major facilitator superfamily domain-containing protein 10

1

9

High-throughput

0.407

High

1195626

Q4LE60
TNPO2 variant protein

1

10

High-throughput

0.407

High

1228652

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

1

High-throughput

0.407

High

867793

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

2

0

High-throughput

0.328

High

1204568

PIGG
GPI ethanolamine phosphate transferase 2, catalytic subunit

2

0

High-throughput

0.328

High

1228642

S14L1
SEC14-like protein 1

2

0

High-throughput

0.328

High

1228644

OMA1
Metalloendopeptidase OMA1, mitochondrial

2

0

High-throughput

0.328

High

1228650

TBCD
Tubulin-specific chaperone D

2

0

High-throughput

0.328

High

712110

CO4A5

2

0

High-throughput

0.316

High

1228651

TM222
Transmembrane protein 222

2

0

High-throughput

0.316

High

1228659

ERG28
Ergosterol biosynthetic protein 28 homolog

2

0

High-throughput

0.316

High

63830

PEDS1
Plasmanylethanolamine desaturase 1

1

0

High-throughput

0.279

Low

166930

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.279

Low

343685

GGPPS
Geranylgeranyl pyrophosphate synthase

1

0

High-throughput

0.279

Low

1139010

SNX17
Sorting nexin-17

1

0

High-throughput

0.279

Low

1228631

ZER1
Protein zer-1 homolog

1

0

High-throughput

0.279

Low

1228633

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.279

Low

1228654

RISC
Retinoid-inducible serine carboxypeptidase

1

0

High-throughput

0.279

Low

1197622

MIDN
Midnolin

1

0

High-throughput

0.249

Low

1228637

MINY2
Ubiquitin carboxyl-terminal hydrolase MINDY-2

1

0

High-throughput

0.249

Low

1168516

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.232

Low

1228626

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.232

Low

1228643

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025