HitPredict

Interactor 1: HSP90 (P41887)
Heat shock protein 90 homolog
Gene: swo1

Interactor 2: STI1 (Q9USI5)
Heat shock protein sti1 homolog
Gene: STI1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	23664927
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HSP90~TPR_8
Common GO terms	GO:0005829 - cytosol GO:0006457 - protein folding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 704 Sp			1 591
+	Hs
		174561 HS90B_HUMAN (6-704): 0: 1020: 62.13		OGT1_HUMAN (2-186): 2.68e-19: 94.4: 12.97
+	Hs
		438201 HS90B_HUMAN (6-704): 0: 1020: 62.13		TOM34_HUMAN (3-120): 1.52e-18: 88.7: 27.78
+	Hs
		174556 HS90A_HUMAN (3-704): 0: 1013: 62.17		OGT1_HUMAN (2-186): 2.68e-19: 94.4: 12.97
+	Hs
		431886 HS90A_HUMAN (3-704): 0: 1013: 62.17		TOM34_HUMAN (3-120): 1.52e-18: 88.7: 27.78
+	Hs
		213454 HS90B_HUMAN (6-704): 0: 1020: 62.13		SGTA_HUMAN (221-389): 4.81e-16: 81.4: 25.00
+	Hs
		437930 HS90B_HUMAN (6-704): 0: 1020: 62.13		STIP1_HUMAN (2-298): 7.15e-14: 76.3: 14.80
+	Hs
		213451 HS90A_HUMAN (3-704): 0: 1013: 62.17		SGTA_HUMAN (221-389): 4.81e-16: 81.4: 25.00
+	Mm
		513680 HS90B_MOUSE (6-704): 0: 1023: 62.69		PPP5_MOUSE (244-360): 3.45e-12: 71: 19.49
+	Hs
		438021 HS90B_HUMAN (6-704): 0: 1020: 62.13		PPP5_HUMAN (244-394): 1.05e-12: 72.5: 17.76
+	Hs
		431774 HS90A_HUMAN (3-704): 0: 1013: 62.17		SPAG1_HUMAN (109-366): 1.52e-14: 79: 9.69
+	Hs
		438533 HS90B_HUMAN (6-704): 0: 1020: 62.13		RPAP3_HUMAN (363-581): 4.76e-12: 70.9: 11.28
+	Hs
		111934 K9JA46_HUMAN (3-704): 0: 1013: 62.17		STIP1_HUMAN (2-298): 7.15e-14: 76.3: 14.80
+	Hs
		431574 HS90A_HUMAN (3-704): 0: 1013: 62.17		STIP1_HUMAN (2-298): 7.15e-14: 76.3: 14.80
+	Hs
		111935 K9JA46_HUMAN (3-704): 0: 1013: 62.17		PPP5_HUMAN (244-394): 1.05e-12: 72.5: 17.76
+	Hs
		431681 HS90A_HUMAN (3-704): 0: 1013: 62.17		PPP5_HUMAN (244-394): 1.05e-12: 72.5: 17.76
+	Hs
		432268 HS90A_HUMAN (3-704): 0: 1013: 62.17		RPAP3_HUMAN (363-581): 4.76e-12: 70.9: 11.28
+	Mm
		432427 HS90A_MOUSE (3-704): 0: 1012: 62.36		PPP5_MOUSE (244-360): 3.45e-12: 71: 19.49
+	Hs
		297025 HS90B_HUMAN (6-704): 0: 1020: 62.13		TOM70_HUMAN (210-539): 1.53e-09: 62.8: 10.42
+	Hs
		297024 HS90A_HUMAN (3-704): 0: 1013: 62.17		TOM70_HUMAN (210-539): 1.53e-09: 62.8: 10.42
+	Hs
		431797 HS90A_HUMAN (3-704): 0: 1013: 62.17		IFT88_HUMAN (3-275): 8.75e-09: 60.5: 10.99