Protein: VATC2
V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)

Gene: VATC2, ATP6V1C2
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q8NEY4

Gene Ontology (top 5):
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0016241 - regulation of macroautophagy
GO:0030177 - positive regulation of Wnt signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

276847

VATG1
V-type proton ATPase subunit G 1

5

4

High-throughput

0.919

High

341215

VATG2
V-type proton ATPase subunit G 2

4

4

High-throughput

0.881

High

784798

VATE1
V-type proton ATPase subunit E 1

4

4

High-throughput

0.881

High

1338139

VATE2
V-type proton ATPase subunit E 2

4

4

High-throughput

0.881

High

637046

VATB2
V-type proton ATPase subunit B, brain isoform

5

7

High-throughput

0.712

High

800536

VATA
V-type proton ATPase catalytic subunit A

5

10

High-throughput

0.712

High

637109

VATC1
V-type proton ATPase subunit C 1

4

4

High-throughput

0.683

High

1164256

VATF
V-type proton ATPase subunit F

4

3

High-throughput

0.683

High

583092

VATB1
V-type proton ATPase subunit B, kidney isoform

3

7

High-throughput

0.656

High

1338148

VATD
V-type proton ATPase subunit D

3

3

High-throughput

0.656

High

1338149

STK24
Serine/threonine-protein kinase 24

3

1

High-throughput

0.656

High

62991

POTEF
POTE ankyrin domain family member F

3

0

High-throughput

0.628

High

445667

KCRM
Creatine kinase M-type

3

0

High-throughput

0.628

High

1338138

WASF1
Actin-binding protein WASF1

3

0

High-throughput

0.628

High

1338142

PDC10
Programmed cell death protein 10

3

0

High-throughput

0.628

High

1338146

DMXL1
DmX-like protein 1

4

3

High-throughput

0.623

High

685266

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

948362

KR122
Keratin-associated protein 12-2

2

0

High-throughput

0.580

High

1048921

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

961550

VA0D1
V-type proton ATPase subunit d 1

1

3

High-throughput

0.575

High

1106799

VPP3
V-type proton ATPase 116 kDa subunit a 3

1

12

High-throughput

0.575

High

1338141

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

1154682

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.479

High

1232472

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

440640

FYN
Tyrosine-protein kinase Fyn

1

0

High-throughput

0.458

High

1125162

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.458

High

1153724

TOM34
Mitochondrial import receptor subunit TOM34

1

0

High-throughput

0.458

High

1338140

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.458

High

1338145

NEUR2
Sialidase-2

1

0

High-throughput

0.458

High

894035

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

848208

MAGA2
Melanoma-associated antigen 2

1

1

High-throughput

0.437

High

1211643

FBP1L
Formin-binding protein 1-like

1

0

High-throughput

0.426

High

848415

MAGA6
Melanoma-associated antigen 6

1

1

High-throughput

0.407

High

1338137

DMXL2
DmX-like protein 2

1

3

High-throughput

0.407

High

1063450

GOGA2
Golgin subfamily A member 2

4

0

High-throughput

0.367

High

136171

SYT5
Synaptotagmin-5

3

0

High-throughput

0.342

High

1292322

ZC3C1
Zinc finger C3HC-type protein 1

3

0

High-throughput

0.342

High

1208261

SPXN3
Sperm protein associated with the nucleus on the X chromosome N3

2

0

High-throughput

0.316

High

1247797

KLH24
Kelch-like protein 24

2

0

High-throughput

0.316

High

1012904

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.279

Low

1328098

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.279

Low

66243

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.249

Low

317349

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.249

Low

372618

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

733397

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.249

Low

789655

HPCL1
Hippocalcin-like protein 1

1

0

High-throughput

0.249

Low

1181327

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.249

Low

1338144

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1338143

ROGDI
Protein rogdi homolog

1

0

High-throughput

0.232

Low

1338147

WDR7
WD repeat-containing protein 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025