HitPredict

Interactor 1: STAT1 (P42225)
Signal transducer and activator of transcription 1
Gene: STAT1

Interactor 2: PML (Q60953)
Protein PML
Gene: PML

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17121994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 749 Mm			1 885
+	Hs
		668490 STAT1_HUMAN (1-749): 0: 1029: 92.27		PML_HUMAN (12-876): 0: 822: 68.77
+	Hs
		668483 STAT3_HUMAN (1-739): 0: 886: 52.01		PML_HUMAN (12-876): 0: 822: 68.77
+	Hs
		668536 STAT2_HUMAN (1-741): 0: 788: 42.65		PML_HUMAN (12-876): 0: 822: 68.77
+	Hs
		786334 STAT1_HUMAN (1-749): 0: 1029: 92.27		TIF1B_HUMAN (16-619): 9.17e-68: 243: 15.72
+	Hs
		786346 STAT1_HUMAN (1-749): 0: 1029: 92.27		TRI25_HUMAN (56-370): 1.37e-48: 185: 16.07
+	Hs
		776670 STAT3_HUMAN (1-739): 0: 886: 52.01		TIF1B_HUMAN (16-619): 9.17e-68: 243: 15.72
+	Hs
		584894 STAT1_HUMAN (1-749): 0: 1029: 92.27		RO52_HUMAN (130-473): 3.67e-19: 93.5: 11.94
+	Hs
		776822 STAT3_HUMAN (1-739): 0: 886: 52.01		TRI45_HUMAN (62-442): 4.75e-64: 228: 18.03
+	Hs
		170287 STAT3_HUMAN (1-739): 0: 886: 52.01		TIF1A_HUMAN (36-558): 2.68e-59: 221: 15.26
+	Hs
		1029430 STAT4_HUMAN (1-740): 0: 863: 52.22		TIF1B_HUMAN (16-619): 9.17e-68: 243: 15.72
+	Hs
		786479 STAT6_HUMAN (1-741): 0: 643: 25.32		TIF1B_HUMAN (16-619): 9.17e-68: 243: 15.72
+	Hs
		170290 STAT6_HUMAN (1-741): 0: 643: 25.32		TIF1A_HUMAN (36-558): 2.68e-59: 221: 15.26
+	Mm
		1143658 Q8CFQ1_MOUSE (518-749): 4.85e-125: 374: 95.69		RO52_MOUSE (44-472): 1.8e-51: 189: 10.61