HitPredict

Interactor 1: STAT3 (P42227)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: JAK2 (Q62120)
Tyrosine-protein kinase JAK2 (EC 2.7.10.2) (Janus kinase 2) (JAK-2)
Gene: JAK2

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 15143188, 21102457, 22402124, 8923468
Identification Methods affinity chromatography technology, enzymatic study, biochemical
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_F1~SH2, PK_Tyr_Ser-Thr~SH2, SH2~SH2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 14 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 770
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024