HitPredict

Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: WDR82 (Q6UXN9)
WD repeat-containing protein 82
Gene: WDR82

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.714

Property	Details
Experiments	20516061, 27880917, 28330616, 30344098, 24366813
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus GO:0072357 - PTW/PP1 phosphatase complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 313
+	Hs
		967809 PP1A_HUMAN (1-323): 0: 579: 90.66		WDR82_HUMAN (1-313): 4e-84: 257: 100.00
+	Hs
		968350 PP1B_HUMAN (1-322): 0: 560: 86.89		WDR82_HUMAN (1-313): 4e-84: 257: 100.00
+	Sc
		743182 PP12_YEAST (3-304): 0: 550: 85.76		SWD2_YEAST (1-308): 7.6e-73: 229: 31.89
+	Hs
		786769 PP1G_HUMAN (1-323): 0: 603: 100.00		SNR40_HUMAN (135-313): 5.97e-40: 144: 13.89
+	Sp
		567155 PP11_SCHPO (7-322): 0: 555: 82.92		YIQ4_SCHPO (7-309): 3.5e-49: 168: 30.91
+	Hs
		967904 PP1A_HUMAN (1-323): 0: 579: 90.66		SNR40_HUMAN (135-313): 5.97e-40: 144: 13.89
+	Hs
		786764 PP1G_HUMAN (1-323): 0: 603: 100.00		FBXW7_HUMAN (175-312): 5.23e-26: 110: 20.29
+	Hs
		964800 PP1B_HUMAN (1-322): 0: 560: 86.89		WDR5_HUMAN (178-311): 1.84e-35: 132: 20.90
+	Dm
		559076 PP12_DROME (5-303): 0: 551: 93.31		WDR82_DROME (44-312): 3.7e-38: 138: 16.49
+	Hs
		786513 PP1G_HUMAN (1-323): 0: 603: 100.00		GBB2_HUMAN (76-267): 8.18e-15: 75.9: 28.21
+	Hs
		786663 PP1G_HUMAN (1-323): 0: 603: 100.00		A16L1_HUMAN (16-292): 3.06e-14: 75.1: 21.71
+	Mm
		989698 PP1G_MOUSE (1-323): 0: 602: 99.69		A16L1_MOUSE (16-292): 1.33e-13: 73.2: 22.78
+	Hs
		968400 PP1B_HUMAN (1-322): 0: 560: 86.89		FBXW7_HUMAN (175-312): 5.23e-26: 110: 20.29
+	Hs
		967798 PP1A_HUMAN (1-323): 0: 579: 90.66		A16L1_HUMAN (16-292): 3.06e-14: 75.1: 21.71
+	Mm
		968152 PP1A_MOUSE (1-323): 0: 579: 90.36		A16L1_MOUSE (16-292): 1.33e-13: 73.2: 22.78
+	Hs
		968339 PP1B_HUMAN (1-322): 0: 560: 86.89		A16L1_HUMAN (16-292): 3.06e-14: 75.1: 21.71
+	Mm
		968508 PP1B_MOUSE (1-322): 0: 560: 86.89		A16L1_MOUSE (16-292): 1.33e-13: 73.2: 22.78