Protein: SWD2
COMPASS component SWD2 (Complex proteins associated with SET1 protein SWD2) (Set1C component SWD2)

Gene: SWD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P36104

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

781134

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

17

20

Small-scale

0.988

High

781160

CFT1
Protein CFT1

5

16

Small-scale

0.925

High

781130

SWD3
COMPASS component SWD3

5

19

Small-scale

0.919

High

781144

PFS2
Polyadenylation factor subunit 2

5

19

Small-scale

0.919

High

781158

YTH1
mRNA 3'-end-processing protein YTH1

4

4

Small-scale

0.892

High

781138

SWD1
COMPASS component SWD1

3

20

Small-scale

0.867

High

781145

BRE2
COMPASS component BRE2

10

7

Small-scale

0.753

High

781153

PTA1
Pre-tRNA-processing protein PTA1

9

1

Small-scale

0.751

High

743182

PP12
Serine/threonine-protein phosphatase PP1-2

8

14

Small-scale

0.750

High

781155

SPP1
COMPASS component SPP1

7

8

Small-scale

0.746

High

781162

SYC1
Protein SYC1

7

2

Small-scale

0.745

High

776463

MPE1
Protein MPE1

6

2

Small-scale

0.732

High

781159

YSH1
Endoribonuclease YSH1

6

8

Small-scale

0.732

High

781163

CFT2
Cleavage factor two protein 2

6

7

Small-scale

0.729

High

781146

FIP1
Pre-mRNA polyadenylation factor FIP1

6

3

Small-scale

0.727

High

781143

REF2
RNA end formation protein 2

8

0

Small-scale

0.718

High

781148

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

5

1

Small-scale

0.709

High

632657

DBP4
ATP-dependent RNA helicase HCA4

1

17

High-throughput

0.691

High

671410

RNA14
mRNA 3'-end-processing protein RNA14

1

19

High-throughput

0.691

High

712917

PAP
Poly(A) polymerase

4

3

Small-scale

0.687

High

626689

HSP60
Heat shock protein 60, mitochondrial

2

20

High-throughput

0.679

High

781140

PTI1
Protein PTI1

4

0

Small-scale

0.649

High

438531

UBC2
Ubiquitin-conjugating enzyme E2 2

1

4

Small-scale

0.647

High

781156

SDC1
COMPASS component SDC1

3

0

High-throughput

0.616

High

781131

SHG1
COMPASS component SHG1

2

0

Small-scale

0.585

High

706791

TF2B
Transcription initiation factor IIB

2

3

Small-scale

0.584

High

382031

H4
Histone H4

1

7

High-throughput

0.575

High

419698

H2A2
Histone H2A.2

1

6

High-throughput

0.575

High

781129

SWD2
COMPASS component SWD2

1

19

High-throughput

0.575

High

781166

MEX67
mRNA export factor MEX67

1

5

Small-scale

0.552

High

781142

SSB2
Ribosome-associated molecular chaperone SSB2

2

18

High-throughput

0.552

High

721846

XPO1
Exportin-1

1

14

High-throughput

0.536

High

781152

H3
Histone H3

1

12

Small-scale

0.527

High

781157

DOT1
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

6

Small-scale

0.515

High

781165

YRA1
RNA annealing protein YRA1

1

9

High-throughput

0.515

High

781161

BRE1
E3 ubiquitin-protein ligase BRE1

1

20

Small-scale

0.501

High

709697

BMH1
Protein BMH1

1

4

High-throughput

0.500

High

401970

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

10

Small-scale

0.479

High

594317

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

738815

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

Small-scale

0.479

High

781151

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

781154

NOP3
Serine/arginine

1

19

Small-scale

0.479

High

781164

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

585256

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.470

High

672100

PUF4
Pumilio homology domain family member 4

1

3

High-throughput

0.470

High

738091

MYO4
Myosin-4

1

6

High-throughput

0.470

High

781139

RV167
Reduced viability upon starvation protein 167

1

6

High-throughput

0.470

High

367735

ENO1
Enolase 1

1

3

High-throughput

0.457

High

392558

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.445

High

523617

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

526406

HSP72
Heat shock protein SSA2

1

19

High-throughput

0.445

High

544475

SSB1
Ribosome-associated molecular chaperone SSB1

1

18

High-throughput

0.445

High

741362

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

781133

SSZ1
Ribosome-associated complex subunit SSZ1

1

18

High-throughput

0.445

High

781137

CAJ1
Protein CAJ1

1

9

High-throughput

0.445

High

781150

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

781135

ADY1
Prospore formation at selected spindle poles protein 1

1

0

Small-scale

0.426

High

781149

H1
Histone H1

1

0

High-throughput

0.426

High

781136

CH10
10 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.407

High

781141

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.407

High

781132

YHI9
Uncharacterized isomerase YHI9

1

0

High-throughput

0.269

Low

572558

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

781147

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025