HitPredict

Interactor 1: FLT3 (P36888)
Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
Gene: FLT3

Interactor 2: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 993 Hs			1 317
+	Hs
		786980 FLT3_HUMAN (1-993): 0: 826: 96.41		LIS1_HUMAN (144-316): 1.51e-45: 160: 23.43
+	Hs
		609981 VGFR1_HUMAN (74-533): 6.71e-35: 146: 14.26		RACK1_HUMAN (1-317): 4.84e-109: 321: 100.00
+	Hs
		179603 MUSK_HUMAN (6-243): 6.9e-29: 126: 13.22		RACK1_HUMAN (1-317): 4.84e-109: 321: 100.00
+	Hs
		609960 VGFR1_HUMAN (74-533): 6.71e-35: 146: 14.26		LIS1_HUMAN (144-316): 1.51e-45: 160: 23.43
+	Hs
		650078 FGFR3_HUMAN (14-355): 2.58e-17: 89.4: 8.59		LIS1_HUMAN (144-316): 1.51e-45: 160: 23.43