HitPredict

Interactor 1: EPS15 (P42566)
Epidermal growth factor receptor substrate 15 (Protein Eps15) (Protein AF-1p)
Gene: EPS15

Interactor 2: KRT83 (P78385)
Keratin, type II cuticular Hb3 (Hair keratin K2.10) (Keratin-83) (K83) (Type II hair keratin Hb3) (Type-II keratin Kb23)
Gene: KRT83

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 896 Hs			1 493
+	Hs
		517742 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C3_HUMAN (83-427): 6.22e-161: 471: 57.02
+	Hs
		380575 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C1_HUMAN (80-436): 1.01e-124: 379: 54.60
+	Hs
		213932 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT86_HUMAN (1-486): 1e-111: 341: 90.14
+	Hs
		787893 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT85_HUMAN (1-479): 1.25e-102: 318: 80.69
+	Hs
		787940 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C73_HUMAN (2-487): 2.4e-96: 303: 44.27
+	Hs
		787979 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT82_HUMAN (1-490): 8.04e-89: 282: 54.80
+	Hs
		318787 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C75_HUMAN (1-425): 2e-85: 275: 47.53
+	Hs
		787928 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C79_HUMAN (10-433): 4.45e-81: 263: 46.03
+	Hs
		531538 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C5_HUMAN (76-425): 1.12e-73: 245: 58.81
+	Hs
		359470 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K2C6A_HUMAN (76-425): 1.19e-72: 242: 57.96
+	Hs
		787912 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		K1H2_HUMAN (8-422): 1.12e-67: 225: 23.87
+	Hs
		787956 EPS15_HUMAN (1-896): 5.15e-160: 493: 100.00		KRT35_HUMAN (8-486): 2.54e-65: 219: 23.75