Interactor 1: AF9 (P42568)
Protein AF-9 (ALL1-fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3)
Gene: MLLT3

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 33961781, 21873227, 20431927, 20854876, 21729782, 20203130
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains YEATS~YEATS
Common GO terms GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008023 - transcription elongation factor complex
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 568
Hs

1 559
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Sc
+ Sp
+ Dm
+ Sc
+ Dm

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Last updated: 15 Jul 2024