Interactor 1: CASP3 (P42574)
Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12]
Gene: CASP3

Interactor 2: ATG4D (Q86TL0)
Cysteine protease ATG4D (EC 3.4.22.-) (AUT-like 4 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 4) (Autophagin-4) (Autophagy-related protein 4 homolog D) (HsAPG4D) [Cleaved into: Cysteine protease ATG4D, mitochondrial]
Gene: ATG4D

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.569

The method score is based on:

Property Details
Experiments 19549685
Identification Methods enzymatic study, protease assay
Interaction Type direct interaction, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004197 - cysteine-type endopeptidase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0006915 - apoptotic process
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 277
Hs

1 474
+ Hs

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Last updated: 15 Jul 2024