HitPredict

Interactor 1: I12R1 (P42701)
Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
Gene: IL12RB1

Interactor 2: CREL2 (Q6UXH1)
Protein disulfide isomerase CRELD2 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 2)
Gene: CRELD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EGF_CA~fn3
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 353
+	Hs
		265776 CRLF1_HUMAN (44-239): 6.07e-41: 156: 18.72		NPNT_HUMAN (204-345): 2.82e-11: 66.4: 22.87
+	Dm
		53734 A1Z920_DROME (223-657): 3.05e-33: 139: 13.23		TENM_DROME (176-346): 4.1e-14: 76: 13.20
+	Dm
		51867 A1Z6X2_DROME (220-533): 2.89e-18: 92: 13.89		TENM_DROME (176-346): 4.1e-14: 76: 13.20
+	Dm
		246777 DSCA1_DROME (220-533): 3.2e-18: 91.6: 13.89		TENM_DROME (176-346): 4.1e-14: 76: 13.20
+	Hs
		489894 PTPRF_HUMAN (288-660): 2.98e-20: 98.2: 11.97		NID1_HUMAN (88-230): 5.55e-12: 69: 11.47