HitPredict

Interactor 1: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 779
+	Hs
		60417 POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		257697 ANR17_HUMAN (69-147): 2.99e-19: 85.1: 20.25		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		596371 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		965125 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1021392 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1021414 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		556699 ANK1_HUMAN (2-130): 2.4e-33: 125: 24.62		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		965158 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1167443 ANR50_HUMAN (26-149): 1.07e-26: 106: 26.61		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		790911 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		1153256 POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1021423 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		RHG22_HUMAN (29-181): 1.62e-33: 139: 26.95
+	Hs
		787145 CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27
+	Hs
		965179 ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		299252 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		FARP2_HUMAN (5-183): 2.45e-30: 130: 21.69
+	Hs
		299289 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		FARP2_HUMAN (5-183): 2.45e-30: 130: 21.69
+	Hs
		1021479 ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		883686 RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		1330900 Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		787164 POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27