HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: ARL16 (Q0P5N6)
ADP-ribosylation factor-like protein 16
Gene: ARL16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 197
+	Hs
		791242 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARF3_HUMAN (1-196): 6.17e-76: 227: 26.13
+	Hs
		791290 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARF1_HUMAN (1-196): 4.8e-76: 227: 25.63
+	Hs
		791254 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARF6_HUMAN (12-195): 7.42e-74: 222: 27.27
+	Hs
		791291 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARF5_HUMAN (1-196): 2.01e-73: 221: 26.13
+	Hs
		791257 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RAB1A_HUMAN (18-196): 8.62e-68: 207: 19.34
+	Hs
		791709 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RAB1B_HUMAN (18-196): 1.15e-67: 207: 19.34
+	Hs
		791191 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RAB5C_HUMAN (1-197): 2.96e-64: 199: 16.58
+	Hs
		631093 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		RAB5A_HUMAN (6-197): 2.06e-63: 196: 15.46