HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: CNN3 (Q15417)
Calponin-3 (Calponin, acidic isoform)
Gene: CNN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	36634849, 39079530
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0015629 - actin cytoskeleton
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 329
+	Hs
		791651 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CNN2_HUMAN (2-311): 2.33e-116: 340: 65.48
+	Hs
		791812 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		TAGL3_HUMAN (5-188): 6.15e-64: 202: 43.37
+	Hs
		790867 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		TAGL2_HUMAN (5-188): 1.4e-61: 196: 42.86
+	Hs
		791305 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		TAGL_HUMAN (5-188): 1.25e-61: 196: 44.16
+	Hs
		791370 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		IQGA2_HUMAN (13-171): 3.2e-37: 143: 16.48