Protein: CNN2
Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin)

Gene: CNN2
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q99439

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005516 - calmodulin binding
GO:0005576 - extracellular region
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1148315

CNN3
Calponin-3

3

12

High-throughput

0.861

High

389486

FINC
Fibronectin

1

4

High-throughput

0.691

High

537762

HSP7C
Heat shock cognate 71 kDa protein

4

4

High-throughput

0.691

High

953052

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.618

High

995783

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.618

High

1255193

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

1404146

CNN2
Calponin-2

1

12

High-throughput

0.618

High

1404155

TES
Testin

1

15

High-throughput

0.618

High

564262

CFTR
Cystic fibrosis transmembrane conductance regulator

2

7

High-throughput

0.611

High

332335

ATE1
Arginyl-tRNA--protein transferase 1

3

1

High-throughput

0.609

High

567749

HEM2
Delta-aminolevulinic acid dehydratase

2

0

High-throughput

0.585

High

1404157

NAGK
N-acetyl-D-glucosamine kinase

2

1

High-throughput

0.574

High

1260478

MTSS2
Protein MTSS 2

1

1

High-throughput

0.536

High

1381468

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

630947

RAB4A
Ras-related protein Rab-4A

1

6

High-throughput

0.489

High

1404150

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.489

High

157763

CTRO
Citron Rho-interacting kinase

1

10

High-throughput

0.479

High

242682

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

315918

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

346226

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

401348

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

556297

CADH1
Cadherin-1

1

7

High-throughput

0.479

High

696300

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

791651

SYUA
Alpha-synuclein

1

5

High-throughput

0.479

High

799425

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

862399

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

891757

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.479

High

1035859

KIF23
Kinesin-like protein KIF23

1

5

High-throughput

0.479

High

1115946

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.479

High

1138537

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

1276687

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1363826

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1404154

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

749990

KINH
Kinesin-1 heavy chain

1

0

High-throughput

0.458

High

948910

CD81
CD81 antigen

1

0

High-throughput

0.458

High

931075

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.445

High

1315704

DND1
Dead end protein homolog 1

1

3

High-throughput

0.445

High

1404148

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

247414

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

8

High-throughput

0.437

High

589490

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.437

High

607029

CEBPB
CCAAT/enhancer-binding protein beta

1

4

High-throughput

0.437

High

685695

U2AF2
Splicing factor U2AF 65 kDa subunit

1

4

High-throughput

0.437

High

768973

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

970953

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.437

High

976506

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.437

High

1108073

SQSTM
Sequestosome-1

1

4

High-throughput

0.437

High

1197545

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

6

High-throughput

0.437

High

1290943

TAXB1
Tax1-binding protein 1

1

14

High-throughput

0.437

High

1350421

BICD2
Protein bicaudal D homolog 2

1

15

High-throughput

0.437

High

1367091

ESR2
Estrogen receptor beta

1

10

High-throughput

0.437

High

1404147

TRI31
E3 ubiquitin-protein ligase TRIM31

1

15

High-throughput

0.437

High

1404149

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.437

High

1404152

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.437

High

1404156

UBQL2
Ubiquilin-2

1

2

High-throughput

0.437

High

1404160

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

369205

OAS1
2'-5'-oligoadenylate synthase 1

1

0

High-throughput

0.426

High

733856

CDD
Cytidine deaminase

1

0

High-throughput

0.426

High

142398

PEX7
Peroxisomal targeting signal 2 receptor

1

4

High-throughput

0.407

High

967170

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

2

High-throughput

0.407

High

1007767

RAE1L
mRNA export factor RAE1

1

4

High-throughput

0.407

High

1227322

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.407

High

1234918

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.407

High

1404151

DDX28
Probable ATP-dependent RNA helicase DDX28

1

2

High-throughput

0.407

High

1404158

GAB2
GRB2-associated-binding protein 2

1

7

High-throughput

0.407

High

1404153

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.279

Low

1404159

TPPC4
Trafficking protein particle complex subunit 4

1

0

High-throughput

0.279

Low

1400435

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.249

Low

1382655

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025