HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: HSPB2 (Q16082)
Heat shock protein beta-2 (HspB2) (DMPK-binding protein) (MKBP) (Heat shock protein family B member 2)
Gene: HSPB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21905118
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 182
+	Hs
		384633 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		CRYAB_HUMAN (6-174): 1e-54: 172: 35.67
+	Hs
		415395 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		HSPB1_HUMAN (1-179): 4.45e-54: 172: 32.85
+	Hs
		156386 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		HSPB6_HUMAN (6-144): 2.25e-41: 138: 40.28
+	Hs
		791819 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		HSPB8_HUMAN (1-170): 4.73e-38: 130: 25.00