HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: TMPSC (Q86WS5)
Transmembrane protease serine 12 (EC 3.4.21.-)
Gene: TMPRSS12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 348
+	Hs
		366336 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		PLMN_HUMAN (30-320): 1.58e-101: 318: 30.17
+	Hs
		457951 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		TRY1_HUMAN (71-321): 8.02e-108: 316: 31.75
+	Hs
		366537 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		TPA_HUMAN (9-319): 1.58e-99: 306: 26.30