HitPredict

Interactor 1: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Interactor 2: ARFG1 (Q8N6T3)
ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)
Gene: ARFGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	39079530, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 406
+	Hs
		791745 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARFG3_HUMAN (1-404): 5.59e-75: 244: 21.13
+	Hs
		791536 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ARFG2_HUMAN (3-404): 6.42e-73: 238: 18.88
+	Hs
		791569 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		SMAP2_HUMAN (5-356): 1.14e-65: 217: 14.40
+	Hs
		791393 SYUA_HUMAN (1-140): 1e-57: 177: 100.00		ACAP1_HUMAN (9-384): 3.08e-62: 215: 12.93