Protein: ARFG3
ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)

Gene: ARFG3, ARFGAP3
Organism: Homo sapiens
Interactions: 128
UniProt ID: Q9NP61

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005096 - GTPase activator activity
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1307649

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.752

High

1329355

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

13

High-throughput

0.691

High

896890

DYN2
Dynamin-2

1

2

High-throughput

0.665

High

1392919

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

1

High-throughput

0.628

High

1324487

AN36B
Ankyrin repeat domain-containing protein 36B

1

4

High-throughput

0.618

High

612312

ARF4
ADP-ribosylation factor 4

1

20

High-throughput

0.618

High

958821

ARF3
ADP-ribosylation factor 3

1

20

High-throughput

0.618

High

1014966

ARF1
ADP-ribosylation factor 1

1

20

High-throughput

0.618

High

1015129

ARF5
ADP-ribosylation factor 5

1

20

High-throughput

0.618

High

791745

SYUA
Alpha-synuclein

2

4

High-throughput

0.606

High

604227

CXA1
Gap junction alpha-1 protein

2

4

High-throughput

0.601

High

844009

HD
Huntingtin

2

4

High-throughput

0.601

High

630986

RAB4A
Ras-related protein Rab-4A

2

5

High-throughput

0.584

High

976582

RB11A
Ras-related protein Rab-11A

2

6

High-throughput

0.584

High

1158786

SYPL1
Synaptophysin-like protein 1

2

0

High-throughput

0.580

High

1359810

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

2

0

High-throughput

0.580

High

396999

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

564404

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

867436

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

1089269

TRI26
Tripartite motif-containing protein 26

1

1

High-throughput

0.536

High

1161226

MK06
Mitogen-activated protein kinase 6

1

6

High-throughput

0.536

High

1417886

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

1445858

ALK
ALK tyrosine kinase receptor

2

20

High-throughput

0.533

High

471560

CD14
Monocyte differentiation antigen CD14

1

0

High-throughput

0.518

High

47421

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.515

High

231765

PEX1
Peroxisomal ATPase PEX1

1

3

High-throughput

0.515

High

384555

CRYAA
Alpha-crystallin A chain

1

6

High-throughput

0.515

High

415878

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.515

High

451275

NFL
Neurofilament light polypeptide

1

5

High-throughput

0.515

High

631699

RAB6A
Ras-related protein Rab-6A

1

10

High-throughput

0.515

High

789023

TGFR2
TGF-beta receptor type-2

1

2

High-throughput

0.515

High

876186

TCPE
T-complex protein 1 subunit epsilon

1

5

High-throughput

0.515

High

931605

RD23A
UV excision repair protein RAD23 homolog A

1

4

High-throughput

0.515

High

1445860

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

1435324

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

423235

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

167654

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.493

High

716355

PRDX6
Peroxiredoxin-6

1

0

High-throughput

0.493

High

927145

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

954621

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1124058

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.493

High

1445861

BACE2
Beta-secretase 2

1

0

High-throughput

0.493

High

706322

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1178893

CF184
Cilia- and flagella-associated protein 184

1

3

High-throughput

0.489

High

1228721

C102B
Coiled-coil domain-containing protein 102B

1

1

High-throughput

0.489

High

140000

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.479

High

173404

XPO1
Exportin-1

1

13

High-throughput

0.479

High

174107

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.479

High

180060

BET1
BET1 homolog

1

6

High-throughput

0.479

High

218809

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

226218

STX6
Syntaxin-6

1

6

High-throughput

0.479

High

327464

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

377735

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

465659

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

475008

VIME
Vimentin

1

5

High-throughput

0.479

High

488871

FURIN
Furin

1

2

High-throughput

0.479

High

541702

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

630643

RAB3B
Ras-related protein Rab-3B

1

7

High-throughput

0.479

High

631493

RAB5A
Ras-related protein Rab-5A

1

8

High-throughput

0.479

High

648691

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

696578

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

715795

MARCS
Myristoylated alanine-rich C-kinase substrate

1

5

High-throughput

0.479

High

895082

EMD
Emerin

1

1

High-throughput

0.479

High

902092

RAB9A
Ras-related protein Rab-9A

1

9

High-throughput

0.479

High

945104

RAB25
Ras-related protein Rab-25

1

6

High-throughput

0.479

High

951449

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

955631

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

962519

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

1015814

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1041311

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1087304

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

1108178

SQSTM
Sequestosome-1

1

6

High-throughput

0.479

High

1125678

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.479

High

1143274

PLEC
Plectin

1

1

High-throughput

0.479

High

1229096

RNF43
E3 ubiquitin-protein ligase RNF43

1

4

High-throughput

0.479

High

1252245

SYNE3
Nesprin-3

1

1

High-throughput

0.479

High

1255647

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

1312267

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

1334014

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1350458

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.479

High

1381527

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

4

High-throughput

0.479

High

1391184

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

1401711

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

4

High-throughput

0.479

High

1414463

DERL1
Derlin-1

1

1

High-throughput

0.479

High

1436322

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1445850

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

1445853

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1445854

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

1445855

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

1445856

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1211280

SNPC4
snRNA-activating protein complex subunit 4

1

2

High-throughput

0.470

High

63338

A5D8W4
Cadherin-1

1

4

High-throughput

0.470

High

853415

CBX5
Chromobox protein homolog 5

1

1

High-throughput

0.470

High

1309023

Q8IVP1
SH3-domain GRB2-like 3, isoform CRA_a

1

2

High-throughput

0.470

High

213655

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.458

High

418450

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

991939

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1256600

CE128
Centrosomal protein of 128 kDa

1

0

High-throughput

0.458

High

1401237

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1404227

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1445852

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

1445857

SHPK
Sedoheptulokinase

1

0

High-throughput

0.458

High

1325647

SVOPL
Putative transporter SVOPL

1

4

High-throughput

0.445

High

179641

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

20

High-throughput

0.437

High

412650

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

464061

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

High-throughput

0.437

High

589759

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.437

High

710765

EPHA8
Ephrin type-A receptor 8

1

12

High-throughput

0.437

High

769246

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

777775

VGFR3
Vascular endothelial growth factor receptor 3

1

19

High-throughput

0.437

High

1031553

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.437

High

1157079

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.437

High

1233507

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1293166

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1323006

CXD3
Gap junction delta-3 protein

1

4

High-throughput

0.437

High

1431757

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

1445859

LAMP3
Lysosome-associated membrane glycoprotein 3

1

3

High-throughput

0.437

High

1433032

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

518792

IL8
Interleukin-8

1

0

High-throughput

0.282

High

231272

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.268

Low

301712

WFS1
Wolframin

1

0

High-throughput

0.268

Low

389888

TTHY
Transthyretin

1

0

High-throughput

0.268

Low

654830

PGH1
Prostaglandin G/H synthase 1

1

0

High-throughput

0.268

Low

891042

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.268

Low

895657

SERPH
Serpin H1

1

0

High-throughput

0.268

Low

1369704

KLK6
Kallikrein-6

1

0

High-throughput

0.268

Low

548376

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.249

Low

1445851

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025