HitPredict

Interactor 1: MATR3 (P43243)
Matrin-3
Gene: MATR3

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 29884807
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 847 Hs			1 656
+	Hs
		794058 MATR3_HUMAN (1-847): 0: 1198: 100.00		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		726637 MATR3_HUMAN (1-847): 0: 1198: 100.00		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		321150 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		541085 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		RBP56_HUMAN (109-555): 5.78e-53: 193: 35.05
+	Hs
		540972 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		727085 PTBP2_HUMAN (329-625): 1.45e-85: 284: 15.50		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		320940 PTBP3_HUMAN (333-622): 5.16e-90: 297: 15.39		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		540911 HNRPL_HUMAN (386-644): 2.18e-74: 256: 16.09		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		967178 ZN638_HUMAN (650-843): 4.53e-20: 98.4: 22.97		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		726821 ZN638_HUMAN (650-843): 4.53e-20: 98.4: 22.97		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		118566 RBM20_HUMAN (587-846): 3.96e-23: 107: 20.15		EYA2_HUMAN (27-278): 1.48e-18: 91.3: 20.16