Protein: CLAP2
CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)

Gene: CLAP2, CLASP2
Organism: Homo sapiens
Interactions: 147
UniProt ID: O75122

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000776 - kinetochore
GO:0002162 - dystroglycan binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

270951

CLAP1
CLIP-associating protein 1

2

10

High-throughput

0.789

High

270938

MARE1
Microtubule-associated protein RP/EB family member 1

10

9

Small-scale

0.755

High

270895

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.722

High

270888

1433T
14-3-3 protein theta

4

20

High-throughput

0.699

High

270926

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

270903

GSK3B
Glycogen synthase kinase-3 beta

4

7

High-throughput

0.683

High

270913

1433G
14-3-3 protein gamma

3

20

High-throughput

0.678

High

270919

1433Z
14-3-3 protein zeta/delta

3

20

High-throughput

0.678

High

270948

MARK2
Serine/threonine-protein kinase MARK2

3

4

High-throughput

0.675

High

270916

1433E
14-3-3 protein epsilon

3

2

High-throughput

0.675

High

270870

LYPD3
Ly6/PLAUR domain-containing protein 3

3

2

High-throughput

0.656

High

270932

DCTN1
Dynactin subunit 1

3

10

High-throughput

0.656

High

270961

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

3

1

High-throughput

0.650

High

270889

MARK3
MAP/microtubule affinity-regulating kinase 3

2

4

Small-scale

0.639

High

270924

CENPE
Centromere-associated protein E

2

2

High-throughput

0.628

High

270981

CPAP
Centrosomal P4.1-associated protein

2

1

High-throughput

0.628

High

270863

CLAP2
CLIP-associating protein 2

1

10

High-throughput

0.618

High

270893

CLIP1
CAP-Gly domain-containing linker protein 1

2

11

High-throughput

0.611

High

270925

ID2
DNA-binding protein inhibitor ID-2

2

1

High-throughput

0.611

High

270959

NIN
Ninein

2

6

High-throughput

0.611

High

270975

KLDC3
Kelch domain-containing protein 3

2

3

High-throughput

0.611

High

270976

GORS1
Golgi reassembly-stacking protein 1

2

1

High-throughput

0.611

High

270956

FA43A
Protein FAM43A

3

3

High-throughput

0.599

High

270983

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

2

0

High-throughput

0.585

High

270899

CCNF
Cyclin-F

2

3

High-throughput

0.584

High

270873

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

270875

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

0

High-throughput

0.551

High

270922

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.550

High

270992

PNMA2
Paraneoplastic antigen Ma2

2

3

High-throughput

0.549

High

270905

CCR4
C-C chemokine receptor type 4

1

2

High-throughput

0.541

High

208932

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.536

High

270869

RCBT2
RCC1 and BTB domain-containing protein 2

1

1

High-throughput

0.536

High

270882

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.536

High

270883

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.536

High

270900

LIS1
Platelet-activating factor acetylhydrolase IB subunit beta

1

3

High-throughput

0.536

High

270910

ACTZ
Alpha-centractin

1

1

High-throughput

0.536

High

270912

DCAF7
DDB1- and CUL4-associated factor 7

1

3

High-throughput

0.536

High

270920

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.536

High

270921

TBB4B
Tubulin beta-4B chain

1

2

High-throughput

0.536

High

270929

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

3

High-throughput

0.536

High

270930

DCTN2
Dynactin subunit 2

1

1

High-throughput

0.536

High

270931

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.536

High

270933

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.536

High

270941

FAXC
Failed axon connections homolog

1

1

High-throughput

0.536

High

270949

STRAA
STE20-related kinase adapter protein alpha

1

1

High-throughput

0.536

High

270954

GCC2
GRIP and coiled-coil domain-containing protein 2

1

4

High-throughput

0.536

High

270957

CLIP4
CAP-Gly domain-containing linker protein 4

1

13

High-throughput

0.536

High

270965

WDR48
WD repeat-containing protein 48

1

4

High-throughput

0.536

High

270972

JKIP1
Janus kinase and microtubule-interacting protein 1

1

5

High-throughput

0.536

High

270997

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

1

High-throughput

0.536

High

270940

RC3H1
Roquin-1

2

1

High-throughput

0.533

High

270973

FEZ1
Fasciculation and elongation protein zeta-1

1

1

Small-scale

0.527

High

270968

ESR2
Estrogen receptor beta

2

4

High-throughput

0.521

High

270879

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.518

High

270884

PYGM
Glycogen phosphorylase, muscle form

1

0

High-throughput

0.518

High

270894

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.518

High

270896

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

270877

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

270886

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.513

High

270908

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

270909

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

1

0

High-throughput

0.513

High

270911

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

270936

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

270944

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.513

High

270978

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.513

High

270986

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.513

High

270923

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.501

High

270988

CLIP2
CAP-Gly domain-containing linker protein 2

1

10

Small-scale

0.501

High

270865

HYPM
Huntingtin-interacting protein M

1

1

High-throughput

0.489

High

270866

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

4

High-throughput

0.489

High

270969

CBP
CREB-binding protein

1

3

Small-scale

0.481

High

270990

FEZ2
Fasciculation and elongation protein zeta-2

1

1

Small-scale

0.481

High

156756

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

172322

XPO1
Exportin-1

1

4

High-throughput

0.479

High

238326

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

240258

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

256715

H2B1K
Histone H2B type 1-K

1

8

High-throughput

0.479

High

270864

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

2

High-throughput

0.479

High

270867

DAB1
Disabled homolog 1

1

2

Small-scale

0.479

High

270868

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

270872

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

270874

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

270876

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

270881

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

270887

DNJB1
DnaJ homolog subfamily B member 1

1

3

High-throughput

0.479

High

270897

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

270902

GSK3A
Glycogen synthase kinase-3 alpha

1

7

High-throughput

0.479

High

270906

PLK1
Serine/threonine-protein kinase PLK1

1

4

High-throughput

0.479

High

270915

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

270917

H2B1C
Histone H2B type 1-C/E/F/G/I

1

8

High-throughput

0.479

High

270918

GRB2
Growth factor receptor-bound protein 2

1

5

High-throughput

0.479

High

270927

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

270934

HAPR1
HUWE1-associated protein modifying stress responses 1

1

1

High-throughput

0.479

High

270935

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

270939

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

2

High-throughput

0.479

High

270942

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

270945

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

270952

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.479

High

270963

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

270966

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

270971

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

270974

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

270979

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

270980

RC3H2
Roquin-2

1

4

High-throughput

0.479

High

270984

TRI36
E3 ubiquitin-protein ligase TRIM36

1

6

High-throughput

0.479

High

270987

PD1L1
Programmed cell death 1 ligand 1

1

2

High-throughput

0.479

High

270989

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

270991

XPO7
Exportin-7

1

4

High-throughput

0.479

High

270993

FZR1
Fizzy-related protein homolog

1

5

High-throughput

0.479

High

270994

MARE3
Microtubule-associated protein RP/EB family member 3

1

9

High-throughput

0.479

High

211241

RFOX2
RNA binding protein fox-1 homolog 2

1

0

High-throughput

0.460

High

257290

PAGE4
P antigen family member 4

1

0

High-throughput

0.458

High

270891

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

270892

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

270937

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

270970

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.458

High

270977

LXN
Latexin

1

0

High-throughput

0.458

High

270982

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

270985

SMYD2
N-lysine methyltransferase SMYD2

1

0

High-throughput

0.458

High

270996

ASB3
Ankyrin repeat and SOCS box protein 3

1

0

High-throughput

0.458

High

254674

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

1

High-throughput

0.445

High

270878

HEPS
Serine protease hepsin

1

1

High-throughput

0.445

High

270901

MAGAA
Melanoma-associated antigen 10

1

1

High-throughput

0.445

High

270907

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.445

High

270914

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

2

High-throughput

0.445

High

270943

ARMC6
Armadillo repeat-containing protein 6

1

1

High-throughput

0.445

High

270947

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.445

High

270953

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

3

High-throughput

0.445

High

270967

LPAR1
Lysophosphatidic acid receptor 1

1

3

High-throughput

0.445

High

270995

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.445

High

104937

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

270885

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

270890

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

270898

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

270928

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.437

High

270950

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

270955

CLASR
CLK4-associating serine/arginine rich protein

1

2

High-throughput

0.437

High

270960

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.437

High

270962

ARL10
ADP-ribosylation factor-like protein 10

1

1

High-throughput

0.437

High

270904

GPC3
Glypican-3

1

0

High-throughput

0.426

High

270958

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

270964

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.426

High

87281

OSCRI
SCRIB overlapping open reading frame protein

1

1

High-throughput

0.407

High

270871

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.407

High

270946

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

270880

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025