HitPredict

Interactor 1: H11 (P43275)
Histone H1.1 (H1 VAR.3) (Histone H1a) (H1a)
Gene: H1-1

Interactor 2: CDK5 (P49615)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	31687929
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Mm			1 292
+	Rn
		413197 H1T_RAT (1-201): 3.81e-36: 127: 49.25		Q6P751_RAT (1-292): 3.49e-144: 408: 59.73
+	Rn
		88903 H11_RAT (1-124): 5.9e-25: 99: 92.74		Q6P751_RAT (1-292): 3.49e-144: 408: 59.73
+	Hs
		559328 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK2_HUMAN (1-292): 3.69e-144: 408: 59.39
+	Hs
		558990 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK2_HUMAN (1-292): 3.69e-144: 408: 59.39
+	Hs
		489003 H14_HUMAN (1-117): 1.45e-21: 90.1: 73.50		CDK5_HUMAN (1-292): 9.9e-140: 397: 99.66
+	Hs
		625377 H11_HUMAN (40-145): 6.4e-17: 77.8: 76.15		CDK2_HUMAN (1-292): 3.69e-144: 408: 59.39
+	Hs
		559065 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK5_HUMAN (1-292): 9.9e-140: 397: 99.66
+	Hs
		559654 H12_HUMAN (1-180): 1.1e-20: 87.8: 57.78		CDK5_HUMAN (1-292): 9.9e-140: 397: 99.66
+	Rn
		88899 H11_RAT (1-124): 5.9e-25: 99: 92.74		CDK1_RAT (1-289): 5.25e-135: 385: 56.70
+	Mm
		794656 H15_MOUSE (1-196): 9.52e-22: 90.9: 60.29		CDK2_MOUSE (1-292): 1.25e-136: 391: 51.77
+	Hs
		414717 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK1_HUMAN (1-289): 3.28e-135: 385: 56.01
+	Mm
		794643 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK2_MOUSE (1-292): 1.25e-136: 391: 51.77
+	Hs
		414716 H15_HUMAN (1-117): 1.41e-20: 87.8: 68.64		CDK1_HUMAN (1-289): 3.28e-135: 385: 56.01
+	Mm
		550489 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK2_MOUSE (1-292): 1.25e-136: 391: 51.77
+	Mm
		509472 H11_MOUSE (1-181): 1.43e-19: 84.7: 100.00		CDK1_MOUSE (1-289): 4.84e-134: 383: 56.70
+	Hs
		414874 H11_HUMAN (40-145): 6.4e-17: 77.8: 76.15		CDK1_HUMAN (1-289): 3.28e-135: 385: 56.01
+	Hs
		559352 H13_HUMAN (1-162): 1.31e-23: 95.5: 59.28		CDK7_HUMAN (2-292): 1.3e-126: 366: 45.24
+	Mm
		509461 H12_MOUSE (32-117): 4.78e-17: 78.2: 80.23		CDK1_MOUSE (1-289): 4.84e-134: 383: 56.70
+	Hs
		488949 H14_HUMAN (1-117): 1.45e-21: 90.1: 73.50		CDK7_HUMAN (2-292): 1.3e-126: 366: 45.24
+	Hs
		559612 H12_HUMAN (1-180): 1.1e-20: 87.8: 57.78		CDK7_HUMAN (2-292): 1.3e-126: 366: 45.24