HitPredict

Interactor 1: ATG8 (P38182)
Autophagy-related protein 8 (Autophagy-related ubiquitin-like modifier ATG8) (Cytoplasm to vacuole targeting protein 5)
Gene: ATG8

Interactor 2: PHB1 (P40961)
Prohibitin-1
Gene: PHB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	38958087, 38964378
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 117 Sc			1 287
+	Hs
		952303 GBRL2_HUMAN (1-116): 1.19e-57: 175: 56.03		PHB2_HUMAN (1-287): 5.62e-95: 283: 45.83
+	Hs
		766364 GBRL2_HUMAN (1-116): 1.19e-57: 175: 56.03		PHB1_HUMAN (4-274): 1.82e-91: 273: 52.77
+	Hs
		766837 GBRL1_HUMAN (1-117): 2.21e-56: 172: 54.70		PHB1_HUMAN (4-274): 1.82e-91: 273: 52.77
+	Hs
		1406033 MLP3A_HUMAN (5-116): 3.32e-45: 144: 36.84		PHB2_HUMAN (1-287): 5.62e-95: 283: 45.83
+	Hs
		1406020 MLP3B_HUMAN (2-116): 1.4e-44: 142: 34.19		PHB2_HUMAN (1-287): 5.62e-95: 283: 45.83
+	Sc
		795452 ATG8_YEAST (1-117): 8.13e-60: 180: 100.00		PHB2_YEAST (25-276): 5.86e-79: 243: 55.56
+	Hs
		766846 MLP3A_HUMAN (5-116): 3.32e-45: 144: 36.84		PHB1_HUMAN (4-274): 1.82e-91: 273: 52.77
+	Hs
		766830 MLP3B_HUMAN (2-116): 1.4e-44: 142: 34.19		PHB1_HUMAN (4-274): 1.82e-91: 273: 52.77