Protein: SLA1
Actin cytoskeleton-regulatory complex protein SLA1

Gene: SLA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 224
UniProt ID: P32790

Gene Ontology (top 5):
GO:0000147 - actin cortical patch assembly
GO:0003779 - actin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

697889

YSC84
Protein YSC84

9

20

Small-scale

0.975

High

697958

LSB3
LAS seventeen-binding protein 3

8

20

Small-scale

0.972

High

697888

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

5

14

Small-scale

0.935

High

551353

ABP1
Actin-binding protein

4

8

Small-scale

0.910

High

477190

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

10

Small-scale

0.873

High

697931

RV167
Reduced viability upon starvation protein 167

3

20

Small-scale

0.862

High

697923

BZZ1
Protein BZZ1

2

7

High-throughput

0.802

High

698000

MYO5
Myosin-5

2

6

High-throughput

0.793

High

698028

LAS17
Proline-rich protein LAS17

15

9

Small-scale

0.764

High

697926

END3
Actin cytoskeleton-regulatory complex protein END3

5

8

Small-scale

0.724

High

604372

CLH
Clathrin heavy chain

5

4

Small-scale

0.723

High

698006

BSP1
Protein BSP1

7

0

Small-scale

0.715

High

692210

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

4

11

Small-scale

0.707

High

635272

SYP1
Suppressor of yeast profilin deletion

4

3

Small-scale

0.700

High

697921

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

11

High-throughput

0.698

High

697950

MGA2
Protein MGA2

1

2

High-throughput

0.698

High

697967

INP52
Polyphosphatidylinositol phosphatase INP52

4

4

Small-scale

0.697

High

697894

SLA2
Protein SLA2

4

7

Small-scale

0.697

High

692446

ECM25
Protein ECM25

5

0

High-throughput

0.687

High

697945

PRK1
Actin-regulating kinase PRK1

3

11

Small-scale

0.683

High

697951

GTS1
Protein GTS1

4

6

Small-scale

0.677

High

697908

VRP1
Verprolin

4

16

High-throughput

0.676

High

697981

ARK1
Actin-regulating kinase 1

3

9

Small-scale

0.664

High

697935

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.663

High

698003

ENT2
Epsin-2

3

8

Small-scale

0.661

High

696281

PP12
Serine/threonine-protein phosphatase PP1-2

3

6

Small-scale

0.660

High

697918

ARPC1
Actin-related protein 2/3 complex subunit 1

3

11

Small-scale

0.658

High

697940

HUA1
Proline-rich protein HUA1

3

0

High-throughput

0.643

High

697932

RSP5
E3 ubiquitin-protein ligase RSP5

2

11

Small-scale

0.639

High

623447

KPC1
Protein kinase C-like 1

2

2

High-throughput

0.633

High

493517

HSP72
Heat shock protein SSA2

3

8

Small-scale

0.629

High

697910

AKL1
Serine/threonine-protein kinase AKL1

2

9

Small-scale

0.619

High

697903

MYO3
Myosin-3

1

6

High-throughput

0.618

High

697902

DEF1
RNA polymerase II degradation factor 1

2

4

High-throughput

0.614

High

698023

INP53
Polyphosphatidylinositol phosphatase INP53

2

4

Small-scale

0.614

High

630573

LSB5
LAS seventeen-binding protein 5

2

0

Small-scale

0.613

High

697897

EDE1
EH domain-containing and endocytosis protein 1

2

6

Small-scale

0.613

High

697927

STM1
Suppressor protein STM1

2

1

High-throughput

0.611

High

697980

APP1
Phosphatidate phosphatase APP1

2

0

High-throughput

0.609

High

697977

INN1
Ingression protein 1

2

0

Small-scale

0.605

High

402918

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

2

3

Small-scale

0.595

High

605959

RAD53
Serine/threonine-protein kinase RAD53

2

1

High-throughput

0.595

High

698031

ENT1
Epsin-1

2

5

Small-scale

0.595

High

697971

AP18B
Clathrin coat assembly protein AP180B

2

10

Small-scale

0.594

High

698026

LDB17
Protein LDB17

2

0

Small-scale

0.587

High

697982

MPS1
Serine/threonine-protein kinase MPS1

1

2

High-throughput

0.568

High

697995

STD1
Protein STD1

1

1

High-throughput

0.560

High

599437

VPS1
Vacuolar protein sorting-associated protein 1

1

3

Small-scale

0.552

High

510694

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.552

High

389066

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

4

High-throughput

0.541

High

562204

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.541

High

634941

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

2

High-throughput

0.541

High

653112

MIG1
Regulatory protein MIG1

1

3

High-throughput

0.541

High

686931

MGM1
Dynamin-like GTPase MGM1, mitochondrial

1

3

High-throughput

0.541

High

697898

SCD5
Protein SCD5

1

1

High-throughput

0.541

High

697909

AP2A
AP-2 complex subunit alpha

1

7

High-throughput

0.541

High

697911

ATM
Serine/threonine-protein kinase TEL1

1

3

High-throughput

0.541

High

697912

ATR
Serine/threonine-protein kinase MEC1

1

3

High-throughput

0.541

High

697917

AIM3
Altered inheritance of mitochondria protein 3

1

10

High-throughput

0.541

High

697934

IMB4
Importin subunit beta-4

1

4

High-throughput

0.541

High

697942

VTH1
VPS10 homolog 1

1

1

High-throughput

0.541

High

697943

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

3

High-throughput

0.541

High

697944

NDC80
Kinetochore protein NDC80

1

8

High-throughput

0.541

High

697969

MCM6
DNA replication licensing factor MCM6

1

1

High-throughput

0.541

High

697979

DMA2
E3 ubiquitin-protein ligase DMA2

1

1

High-throughput

0.541

High

697983

ZDS2
Protein ZDS2

1

6

High-throughput

0.541

High

697990

SEN1
Helicase SEN1

1

2

High-throughput

0.541

High

697992

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.541

High

697997

NHP10
Non-histone protein 10

1

19

High-throughput

0.541

High

698010

SPO75
Sporulation-specific protein 75

1

1

High-throughput

0.541

High

698013

MDN1
Midasin

1

2

High-throughput

0.541

High

698014

TGS1
Trimethylguanosine synthase

1

1

High-throughput

0.541

High

471380

RL11A
Large ribosomal subunit protein uL5A

1

3

High-throughput

0.536

High

675908

XPO1
Exportin-1

1

5

High-throughput

0.536

High

697963

RL38
Large ribosomal subunit protein eL38

1

1

High-throughput

0.536

High

419324

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.518

High

419540

RAD1
DNA repair protein RAD1

1

0

High-throughput

0.518

High

429186

SEC4
Ras-related protein SEC4

1

0

Small-scale

0.518

High

525692

ATR1
Aminotriazole resistance protein

1

0

High-throughput

0.518

High

613114

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.518

High

624264

AP2
AP-1-like transcription factor YAP2

1

0

High-throughput

0.518

High

630461

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.518

High

679777

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.518

High

697895

DUR3
Urea active transporter

1

0

High-throughput

0.518

High

697899

CLG1
PHO85 cyclin CLG1

1

0

High-throughput

0.518

High

697905

MUD2
Splicing factor MUD2

1

0

High-throughput

0.518

High

697906

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.518

High

697913

TBS1
Uncharacterized transcriptional regulatory protein TBS1

1

0

High-throughput

0.518

High

697914

KTR3
Probable mannosyltransferase KTR3

1

0

High-throughput

0.518

High

697956

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.518

High

697960

SFH5
Phosphatidylinositol transfer protein SFH5

1

0

High-throughput

0.518

High

697976

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.518

High

697984

VPS9
Vacuolar protein sorting-associated protein 9

1

0

High-throughput

0.518

High

697999

URC2
Uracil catabolism protein 2

1

0

High-throughput

0.518

High

698001

GAL83
SNF1 protein kinase subunit beta-3

1

0

High-throughput

0.518

High

698002

YM87
Uncharacterized membrane protein YMR253C

1

0

High-throughput

0.518

High

698005

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.518

High

698011

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.518

High

698016

HUA2
Protein HUA2

1

0

High-throughput

0.518

High

698025

SCM3
Protein SCM3

1

0

High-throughput

0.518

High

698029

LDB19
Protein LDB19

1

0

High-throughput

0.518

High

698032

CSR2
Transcription factor CSR2

1

0

High-throughput

0.518

High

698033

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.518

High

357646

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

339530

CDK1
Cyclin-dependent kinase 1

1

2

High-throughput

0.501

High

539327

KSS1
Mitogen-activated protein kinase KSS1

1

4

High-throughput

0.501

High

614587

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

614910

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

623803

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

2

High-throughput

0.501

High

688733

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.501

High

693687

IME2
Meiosis induction protein kinase IME2/SME1

1

4

High-throughput

0.501

High

697920

RCK2
Serine/threonine-protein kinase RCK2

1

1

High-throughput

0.501

High

697922

GGA2
ADP-ribosylation factor-binding protein GGA2

1

2

Small-scale

0.501

High

697924

AP18A
Clathrin coat assembly protein AP180A

1

8

Small-scale

0.501

High

697948

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

4

Small-scale

0.501

High

697949

AIM21
Altered inheritance of mitochondria protein 21

1

3

High-throughput

0.501

High

697955

BNI1
Protein BNI1

1

2

High-throughput

0.501

High

697996

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

4

High-throughput

0.501

High

698024

PRR2
Serine/threonine-protein kinase PRR2

1

4

High-throughput

0.501

High

357479

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.494

High

635026

YCZ0
Uncharacterized protein YCR100C

1

1

High-throughput

0.494

High

697893

CSE1
Importin alpha re-exporter

1

2

High-throughput

0.494

High

697900

MTH1
Protein MTH1

1

1

High-throughput

0.494

High

697907

GMH1
Protein GMH1

1

1

High-throughput

0.494

High

697975

TDA7
Topoisomerase I damage affected protein 7

1

6

High-throughput

0.494

High

697993

MLP1
Protein MLP1

1

6

High-throughput

0.494

High

698012

FDH1
Formate dehydrogenase 1

1

1

High-throughput

0.494

High

698022

RBD2
Rhomboid-type serine protease 2

1

1

High-throughput

0.494

High

698027

YD206
Putative cation exchanger YDL206W

1

1

High-throughput

0.494

High

698007

TSR2
Pre-rRNA-processing protein TSR2

1

0

High-throughput

0.493

High

404990

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.489

High

697929

RS14B
Small ribosomal subunit protein uS11B

1

2

High-throughput

0.489

High

568297

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.486

High

691149

KRE6
Beta-glucan synthesis-associated protein KRE6

1

0

Small-scale

0.486

High

514542

BIK1
Nuclear fusion protein BIK1

1

1

High-throughput

0.481

High

643162

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

6

Small-scale

0.481

High

680557

HS104
Heat shock protein 104

1

4

Small-scale

0.481

High

419999

STE3
Pheromone a factor receptor

1

0

Small-scale

0.480

High

697991

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

356354

H4
Histone H4

1

7

High-throughput

0.479

High

557964

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

631760

RS2
Small ribosomal subunit protein uS5

1

1

Small-scale

0.479

High

661716

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

664721

BMH1
Protein BMH1

1

4

High-throughput

0.479

High

689319

ARP2
Actin-related protein 2

1

4

High-throughput

0.479

High

697892

ARPC4
Actin-related protein 2/3 complex subunit 4

1

1

High-throughput

0.479

High

697901

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

697904

CENPA
Histone H3-like centromeric protein CSE4

1

20

High-throughput

0.479

High

697915

ATG8
Autophagy-related protein 8

1

5

Small-scale

0.479

High

697919

KPR2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.479

High

697930

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

697947

ARPC5
Actin-related protein 2/3 complex subunit 5

1

1

High-throughput

0.479

High

697954

COPB2
Coatomer subunit beta'

1

5

Small-scale

0.479

High

697961

ARP3
Actin-related protein 3

1

4

High-throughput

0.479

High

697972

COPA
Coatomer subunit alpha

1

5

Small-scale

0.479

High

697973

ARPC2
Actin-related protein 2/3 complex subunit 2

1

1

High-throughput

0.479

High

697986

H3
Histone H3

1

20

High-throughput

0.479

High

697989

NUM1
Nuclear migration protein NUM1

1

9

High-throughput

0.479

High

698004

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.479

High

698018

PSH1
RING finger protein PSH1

1

1

High-throughput

0.479

High

698020

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

698030

CMR1
DNA damage-binding protein CMR1

1

8

High-throughput

0.479

High

697933

FIR1
Factor interacting with REF2

1

0

Small-scale

0.460

High

697968

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.460

High

697985

SLG1
Protein SLG1

1

0

Small-scale

0.460

High

697890

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

697998

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

698008

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

399382

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.445

High

490709

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

498851

RL4A
Large ribosomal subunit protein uL4A

1

5

High-throughput

0.445

High

534719

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.445

High

534924

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.445

High

555924

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

627851

SIS1
Protein SIS1

1

3

High-throughput

0.445

High

694357

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

697928

CAJ1
Protein CAJ1

1

4

High-throughput

0.445

High

697936

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

697941

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

697964

RL4B
Large ribosomal subunit protein uL4B

1

5

High-throughput

0.445

High

697966

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.445

High

698021

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.445

High

697916

MMS4
Crossover junction endonuclease MMS4

1

0

High-throughput

0.438

High

698034

YL363
Uncharacterized protein YLR363W-A

1

0

High-throughput

0.438

High

482686

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.437

High

629799

SYNM
Asparagine--tRNA ligase, mitochondrial

1

4

High-throughput

0.437

High

685497

COPG
Coatomer subunit gamma

1

6

Small-scale

0.437

High

697891

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

697953

COPB
Coatomer subunit beta

1

4

Small-scale

0.437

High

613661

RS3A2
Small ribosomal subunit protein eS1B

1

1

High-throughput

0.407

High

645183

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.407

High

667141

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.407

High

697937

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.407

High

525815

KEX2
Kexin

2

0

Small-scale

0.334

High

698017

PER33
Pore and endoplasmic reticulum protein of 33 kDa

2

0

High-throughput

0.329

High

536671

SNA3
Protein SNA3

2

0

High-throughput

0.317

High

520238

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.282

High

630923

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.282

High

634306

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.282

High

689151

COQ2
4-hydroxybenzoate polyprenyltransferase, mitochondrial

1

0

High-throughput

0.282

High

697896

SPO23
Sporulation protein 23

1

0

High-throughput

0.282

High

697925

GAA1
GPI transamidase component GAA1

1

0

High-throughput

0.282

High

697938

LDO45
Lipid droplet organization protein LDO45

1

0

High-throughput

0.282

High

697939

TGL3
Triacylglycerol lipase 3

1

0

High-throughput

0.282

High

697946

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.282

High

697952

SYS1
Protein SYS1

1

0

High-throughput

0.282

High

697957

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.282

High

697962

YJ85
Uncharacterized protein YJR115W

1

0

High-throughput

0.282

High

697965

ALG10
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

High-throughput

0.282

High

697970

VPS73
Vacuolar protein sorting-associated protein 73

1

0

High-throughput

0.282

High

697978

YNO4
Uncharacterized protein YNL144C

1

0

High-throughput

0.282

High

697994

SMA1
Spore membrane assembly protein 1

1

0

High-throughput

0.282

High

698009

ACK1
Activator of C kinase protein 1

1

0

High-throughput

0.282

High

698015

IOC2
ISWI one complex protein 2

1

0

High-throughput

0.282

High

698019

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

High-throughput

0.282

High

698035

TAR1
Protein TAR1

1

0

High-throughput

0.251

Low

481487

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.249

Low

481883

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

482848

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

697959

COPD
Coatomer subunit delta

1

0

Small-scale

0.249

Low

697974

YN25
Putative uncharacterized protein YNL285W

1

0

High-throughput

0.238

Low

697987

YD413
Putative uncharacterized protein YDR413C

1

0

High-throughput

0.238

Low

697988

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024