HitPredict

Interactor 1: H33 (P84243)
Histone H3.3
Gene: H3-3A

Interactor 2: FOXC1 (Q12948)
Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)
Gene: FOXC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008283 - cell population proliferation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 553
+	Hs
		934709 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		FOXC1_HUMAN (1-553): 8.84e-82: 267: 100.00
+	Hs
		952275 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		FOXK1_HUMAN (73-399): 1.02e-47: 179: 25.93
+	Hs
		934667 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		FOXK2_HUMAN (19-481): 4.43e-47: 176: 22.18
+	Hs
		952278 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		FOXK2_HUMAN (19-481): 4.43e-47: 176: 22.18
+	Hs
		935376 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		FOXJ3_HUMAN (8-471): 6.17e-46: 172: 22.20
+	Hs
		952702 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		FOXJ3_HUMAN (8-471): 6.17e-46: 172: 22.20
+	Hs
		828192 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		FOXK1_HUMAN (73-399): 1.02e-47: 179: 25.93
+	Hs
		828194 CENPA_HUMAN (9-133): 2.42e-45: 146: 50.76		FOXK2_HUMAN (19-481): 4.43e-47: 176: 22.18
+	Hs
		877685 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		FOXA1_HUMAN (14-357): 6.54e-35: 139: 30.52
+	Sc
		762080 H3_YEAST (1-136): 3.62e-54: 168: 90.44		FHL1_YEAST (76-422): 6.8e-37: 148: 15.32
+	Hs
		1035161 H37_HUMAN (1-136): 4.54e-57: 175: 94.12		FOXE3_HUMAN (78-166): 4.72e-26: 110: 66.29