HitPredict

Interactor 1: KSYK (P43405)
Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Gene: SYK

Interactor 2: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22267732
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 635 Hs			1 767
+	Gg
		94471 KSYK_CHICK (3-634): 0: 560: 76.27		SC23A_CHICK (1-766): 0: 1067: 93.21
+	Hs
		872445 EPHA5_HUMAN (171-632): 5.04e-115: 370: 25.42		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		1074039 NTRK2_HUMAN (158-631): 7.36e-116: 366: 24.27		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		508018 FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		665245 EPHA2_HUMAN (242-629): 6.67e-111: 357: 28.83		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		872444 EPHA5_HUMAN (171-632): 5.04e-115: 370: 25.42		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		872652 EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		508017 FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		872651 EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		338466 EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		315673 EPHA5_HUMAN (171-632): 5.04e-115: 370: 25.42		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315638 FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315708 NTRK2_HUMAN (158-631): 7.36e-116: 366: 24.27		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315656 EPHA2_HUMAN (242-629): 6.67e-111: 357: 28.83		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315674 EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315533 EPHA5_HUMAN (171-632): 5.04e-115: 370: 25.42		SC24A_HUMAN (4-760): 0: 559: 19.20
+	Hs
		315512 FGFR1_HUMAN (179-635): 7.43e-116: 366: 26.24		SC24A_HUMAN (4-760): 0: 559: 19.20
+	Hs
		315534 EPHA4_HUMAN (329-626): 1.47e-105: 343: 34.54		SC24A_HUMAN (4-760): 0: 559: 19.20
+	Hs
		315620 EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		315499 EGFR_HUMAN (375-619): 8.73e-57: 209: 43.15		SC24A_HUMAN (4-760): 0: 559: 19.20