HitPredict

Interactor 1: KI2L1 (P43626)
Killer cell immunoglobulin-like receptor 2DL1 (CD158 antigen-like family member A) (Natural killer-associated transcript 1) (NKAT-1) (p58 natural killer cell receptor clones CL-42/47.11) (p58 NK receptor CL-42/47.11) (p58.1 MHC class-I-specific NK receptor) (CD antigen CD158a)
Gene: KIR2DL1

Interactor 2: KI3L1 (P43629)
Killer cell immunoglobulin-like receptor 3DL1 (CD158 antigen-like family member E) (HLA-BW4-specific inhibitory NK cell receptor) (Natural killer-associated transcript 3) (NKAT-3) (p70 natural killer cell receptor clones CL-2/CL-11) (p70 NK receptor CL-2/CL-11) (CD antigen CD158e)
Gene: KIR3DL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ig~ig
Common GO terms	GO:0005886 - plasma membrane GO:0006955 - immune response
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 348 Hs			1 444
+	Hs
		798163 KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54		KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00
+	Hs
		798230 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI3L1_HUMAN (1-444): 1.25e-115: 347: 100.00
+	Hs
		798168 KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54		KI3S1_HUMAN (1-369): 9.59e-97: 297: 95.66
+	Hs
		798164 KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54		KI2S2_HUMAN (1-241): 9.82e-45: 159: 39.22
+	Hs
		798169 KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54		KI2S3_HUMAN (1-241): 1.24e-41: 151: 37.65
+	Hs
		798135 KI2L2_HUMAN (1-348): 3.7e-137: 395: 94.54		KI2L1_HUMAN (1-233): 1.07e-40: 150: 39.17
+	Hs
		798142 KI2L1_HUMAN (1-348): 1.19e-135: 391: 100.00		KI2S3_HUMAN (1-241): 1.24e-41: 151: 37.65
+	Hs
		798180 KI2L3_HUMAN (1-340): 3.49e-131: 379: 90.32		KI2L3_HUMAN (1-241): 1.92e-42: 154: 38.82
+	Hs
		798265 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI2LA_HUMAN (1-219): 2.33e-45: 163: 56.16
+	Hs
		798257 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI2S2_HUMAN (1-241): 9.82e-45: 159: 39.22
+	Hs
		798260 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI2S1_HUMAN (1-241): 2.57e-44: 158: 38.43
+	Hs
		798259 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI2S5_HUMAN (1-241): 5.02e-42: 152: 36.47
+	Hs
		798258 KI2S2_HUMAN (1-303): 1.41e-123: 359: 91.12		KI2S3_HUMAN (1-241): 1.24e-41: 151: 37.65
+	Hs
		1060411 KI2S3_HUMAN (1-303): 4.04e-121: 353: 89.15		KI2S5_HUMAN (1-241): 5.02e-42: 152: 36.47