HitPredict

Interactor 1: KI2L2 (P43627)
Killer cell immunoglobulin-like receptor 2DL2 (CD158 antigen-like family member B1) (Natural killer-associated transcript 6) (NKAT-6) (p58 natural killer cell receptor clone CL-43) (p58 NK receptor CL-43) (CD antigen CD158b1)
Gene: KIR2DL2

Interactor 2: KI2S2 (P43631)
Killer cell immunoglobulin-like receptor 2DS2 (CD158 antigen-like family member J) (NK receptor 183 ActI) (Natural killer-associated transcript 5) (NKAT-5) (p58 natural killer cell receptor clone CL-49) (p58 NK receptor CL-49) (CD antigen CD158j)
Gene: KIR2DS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	ig~ig
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 348 Hs			1 304
+	Hs
		798169 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI2S3_HUMAN (1-304): 7.03e-115: 335: 91.78
+	Hs
		798142 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		KI2S3_HUMAN (1-304): 7.03e-115: 335: 91.78
+	Hs
		798135 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI2L1_HUMAN (1-303): 7.68e-106: 314: 91.09
+	Hs
		798163 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI3L1_HUMAN (1-251): 1.6e-58: 195: 38.58
+	Hs
		798136 KI2L1_HUMAN (1-348): 1.05e-132: 384: 94.54		KI3L1_HUMAN (1-251): 1.6e-58: 195: 38.58
+	Hs
		798168 KI2L2_HUMAN (1-348): 1.32e-134: 388: 100.00		KI3S1_HUMAN (1-251): 4.2e-57: 190: 38.19
+	Hs
		798230 KI3L1_HUMAN (1-346): 5.84e-71: 229: 31.52		KI2S2_HUMAN (1-304): 9.17e-119: 345: 100.00
+	Hs
		47501 A0A8I5QEB2_HUMAN (1-330): 3.52e-69: 224: 33.93		KI2S5_HUMAN (1-304): 2.21e-115: 336: 91.78
+	Hs
		798235 KI3S1_HUMAN (1-346): 8.59e-72: 229: 31.23		KI3L1_HUMAN (1-251): 1.6e-58: 195: 38.58
+	Hs
		252781 LIRB3_HUMAN (1-336): 1.47e-70: 233: 26.02		LIRA6_HUMAN (28-258): 4.97e-39: 144: 34.32
+	Hs
		1232784 LIRB2_HUMAN (17-348): 2.58e-53: 186: 28.70		LIRA3_HUMAN (21-282): 1.61e-40: 148: 32.84
+	Hs
		252771 LIRA3_HUMAN (17-345): 3.4e-52: 180: 28.61		LIRA1_HUMAN (21-246): 2.6e-41: 151: 37.66
+	Hs
		1235887 LIRB1_HUMAN (17-348): 3.13e-51: 182: 28.41		LIRA3_HUMAN (21-282): 1.61e-40: 148: 32.84
+	Hs
		1232785 LIRB4_HUMAN (1-324): 1.6e-77: 246: 29.20		LIRB2_HUMAN (10-138): 5.62e-15: 77.1: 36.43