Protein: BRCA1
Breast cancer type 1 susceptibility protein homolog (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BRCA1)

Gene: BRCA1
Organism: Mus musculus
Interactions: 27
UniProt ID: P48754

Gene Ontology (top 5):
GO:0000152 - nuclear ubiquitin ligase complex
GO:0000724 - double-strand break repair via homologous recombination
GO:0000793 - condensed chromosome
GO:0000794 - condensed nuclear chromosome
GO:0000800 - lateral element

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508974

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

17

High-throughput

0.647

High

877617

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

17

Small-scale

0.647

High

877618

BRCA2
Breast cancer type 2 susceptibility protein homolog

3

4

Small-scale

0.642

High

877621

PALB2
Partner and localizer of BRCA2

2

1

Small-scale

0.571

High

599649

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

9

Small-scale

0.561

High

673994

PO2F1
POU domain, class 2, transcription factor 1

1

6

Small-scale

0.561

High

586086

TFE2
Transcription factor E2-alpha

1

2

High-throughput

0.541

High

724896

HXA2
Homeobox protein Hox-A2

1

5

High-throughput

0.541

High

877624

EWS
RNA-binding protein EWS

1

17

High-throughput

0.541

High

877629

HXC12
Homeobox protein Hox-C12

1

10

High-throughput

0.541

High

877632

OLIG1
Oligodendrocyte transcription factor 1

1

3

High-throughput

0.541

High

877623

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

Small-scale

0.536

High

877627

SUZ12
Polycomb protein Suz12

1

3

Small-scale

0.536

High

877619

NF1
Neurofibromin

1

2

Small-scale

0.501

High

98419

E9QPK4
Serine/threonine-protein kinase ATR

1

17

Small-scale

0.479

High

432070

JUN
Transcription factor Jun

1

15

Small-scale

0.479

High

625740

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

702318

ETV4
ETS translocation variant 4

1

8

Small-scale

0.479

High

877620

RAD51
DNA repair protein RAD51 homolog 1

1

6

Small-scale

0.479

High

877622

ACACA
Acetyl-CoA carboxylase 1

1

12

Small-scale

0.479

High

877625

NPM
Nucleophosmin

1

7

Small-scale

0.479

High

877626

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

15

Small-scale

0.479

High

877628

NANOG
Homeobox protein NANOG

1

7

High-throughput

0.479

High

877630

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

2

Small-scale

0.479

High

877631

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

Small-scale

0.479

High

877633

CAF1A
Chromatin assembly factor 1 subunit A

1

7

High-throughput

0.479

High


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Last updated: 11Aug2025