HitPredict

Interactor 1: CSN1 (P45432)
COP9 signalosome complex subunit 1 (CSN complex subunit 1) (Constitutive photomorphogenesis protein 11) (Protein FUSCA 6)
Gene: CSN1

Interactor 2: CSN5A (Q8LAZ7)
COP9 signalosome complex subunit 5a (Signalosome subunit 5a) (EC 3.4.-.-) (Jun activation domain-binding homolog 1)
Gene: CSN5A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.860

Property	Details
Experiments	9811788, 12615944, 15486099
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	JAB~PCI
Common GO terms	GO:0000338 - protein deneddylation GO:0005737 - cytoplasm GO:0008180 - COP9 signalosome GO:0009585 - red, far-red light phototransduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 441 At			1 357
+	At
		799480 CSN1_ARATH (1-441): 7.1e-135: 396: 100.00		CSN5B_ARATH (1-356): 1.45e-134: 389: 85.71
+	Mm
		102340 G3UXW9_MOUSE (28-440): 4.8e-105: 323: 45.64		CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09
+	Mm
		193526 CSN1_MOUSE (28-440): 5.96e-104: 318: 45.64		CSN5_MOUSE (1-338): 4.4e-123: 359: 65.09
+	Hs
		1024199 CSN1_HUMAN (28-440): 1.81e-100: 310: 45.00		CSN5_HUMAN (1-338): 6.45e-123: 359: 65.09
+	At
		799478 CSN1_ARATH (1-441): 7.1e-135: 396: 100.00		EIF3H_ARATH (40-349): 2.68e-82: 255: 15.39
+	Dm
		1277039 CSN2_DROME (61-427): 2.6e-81: 259: 15.34		CSN5_DROME (6-342): 6.46e-129: 373: 63.80
+	An
		1124330 CSN1_EMENI (6-436): 1.48e-98: 305: 35.62		CSN5_EMENI (8-342): 1.28e-108: 322: 51.63
+	Ce
		954225 CSN1_CAEEL (13-440): 4.45e-80: 260: 24.69		CSN5_CAEEL (5-354): 7.71e-116: 342: 52.57
+	Hs
		130893 PSMD6_HUMAN (32-428): 2.95e-109: 329: 19.35		PSDE_HUMAN (49-312): 3.09e-81: 251: 32.98
+	Dm
		1358521 PSMD6_DROME (31-428): 1.38e-101: 309: 17.54		PSDE_DROME (42-312): 2.1e-83: 257: 33.33
+	Sp
		784775 RPN6_SCHPO (7-430): 2.89e-94: 292: 15.33		RPN11_SCHPO (37-310): 7.7e-76: 237: 29.87
+	Hs
		849202 PSMD6_HUMAN (32-428): 2.95e-109: 329: 19.35		PSMD7_HUMAN (55-281): 1.01e-56: 189: 16.80
+	Dm
		1180711 PSD11_DROME (71-430): 2.51e-80: 256: 14.68		PSDE_DROME (42-312): 2.1e-83: 257: 33.33
+	Sp
		784771 RPN7_SCHPO (49-421): 2.61e-87: 273: 18.25		RPN11_SCHPO (37-310): 7.7e-76: 237: 29.87
+	Sc
		797651 RPN6_YEAST (66-429): 1.84e-85: 270: 14.44		RPN11_YEAST (37-311): 1e-76: 240: 30.41
+	Hs
		121632 PSD11_HUMAN (67-429): 1.25e-80: 257: 14.56		PSDE_HUMAN (49-312): 3.09e-81: 251: 32.98
+	Dm
		640777 PSMD6_DROME (31-428): 1.38e-101: 309: 17.54		PSMD7_DROME (55-290): 1.96e-54: 183: 16.54
+	Hs
		121709 PSD11_HUMAN (67-429): 1.25e-80: 257: 14.56		PSMD7_HUMAN (55-281): 1.01e-56: 189: 16.80
+	Dm
		640773 PSD11_DROME (71-430): 2.51e-80: 256: 14.68		PSMD7_DROME (55-290): 1.96e-54: 183: 16.54
+	Sc
		996269 RPN6_YEAST (66-429): 1.84e-85: 270: 14.44		RPN8_YEAST (57-211): 2.34e-29: 117: 22.79