Protein: ALDR
Aldo-keto reductase family 1 member B1 (EC 1.1.1.300) (EC 1.1.1.372) (EC 1.1.1.54) (Aldehyde reductase) (Aldose reductase) (AR) (EC 1.1.1.21)

Gene: ALDR, AKR1B1
Organism: Homo sapiens
Interactions: 53
UniProt ID: P15121

Gene Ontology (top 5):
GO:0001523 - retinoid metabolic process
GO:0001758 - retinal dehydrogenase activity
GO:0002070 - epithelial cell maturation
GO:0003091 - renal water homeostasis
GO:0004032 - aldose reductase (NADPH) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

87532

AK1BF
Aldo-keto reductase family 1 member B15

3

11

High-throughput

0.848

High

537531

AK1A1
Aldo-keto reductase family 1 member A1

1

13

High-throughput

0.691

High

544733

TERA
Transitional endoplasmic reticulum ATPase

2

4

High-throughput

0.584

High

544756

EFC11
EF-hand calcium-binding domain-containing protein 11

2

1

High-throughput

0.553

High

544743

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.547

High

176372

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

3

High-throughput

0.536

High

544725

TFE3
Transcription factor E3

1

1

High-throughput

0.515

High

544742

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

1

High-throughput

0.515

High

359620

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.513

High

544759

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

544730

APJ
Apelin receptor

1

3

High-throughput

0.494

High

544741

SMAD1
Mothers against decapentaplegic homolog 1

1

0

High-throughput

0.486

High

544735

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

243869

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

300520

NFAT5
Nuclear factor of activated T-cells 5

1

1

Small-scale

0.479

High

544722

DESP
Desmoplakin

1

1

High-throughput

0.479

High

544723

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

544728

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

544729

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

544732

GSK3B
Glycogen synthase kinase-3 beta

1

4

High-throughput

0.479

High

544734

ANM2
Protein arginine N-methyltransferase 2

1

1

Small-scale

0.479

High

544736

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.479

High

544737

DYST
Dystonin

1

2

High-throughput

0.479

High

544738

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

544740

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

544746

ASB18
Ankyrin repeat and SOCS box protein 18

1

1

High-throughput

0.479

High

544747

ASB5
Ankyrin repeat and SOCS box protein 5

1

1

High-throughput

0.479

High

544749

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

544751

ASB9
Ankyrin repeat and SOCS box protein 9

1

2

High-throughput

0.479

High

544754

NECD
Necdin

1

1

High-throughput

0.479

High

544755

BAG1
BAG family molecular chaperone regulator 1

1

1

High-throughput

0.479

High

544757

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.479

High

544761

TRAF6
TNF receptor-associated factor 6

1

1

High-throughput

0.479

High

380934

SHBG
Sex hormone-binding globulin

1

0

Small-scale

0.460

High

354274

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

384205

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

544724

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

544726

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

544727

PAX7
Paired box protein Pax-7

1

0

High-throughput

0.458

High

544731

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

544744

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

544750

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

544760

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

544753

LMTK3
Serine/threonine-protein kinase LMTK3

1

1

High-throughput

0.457

High

496222

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

544739

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

4

High-throughput

0.445

High

544758

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

544745

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

528475

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

544748

BSND
Barttin

1

0

High-throughput

0.279

Low

225507

PCDH7
Protocadherin-7

1

0

High-throughput

0.249

Low

259988

ZN253
Zinc finger protein 253

1

0

High-throughput

0.249

Low

544752

CSMD1
CUB and sushi domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024