HitPredict

Interactor 1: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 3256 Hs			1 904
+	Hs
		708574 KI67_HUMAN (1-3256): 0: 1046: 100.00		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		627206 KI67_HUMAN (1-3256): 0: 1046: 100.00		MCM3_HUMAN (186-897): 0: 725: 29.20
+	Hs
		801141 KI67_HUMAN (1-3256): 0: 1046: 100.00		MCM6_HUMAN (186-817): 0: 710: 31.18
+	Hs
		832603 MUC16_HUMAN (48-2581): 3.63e-63: 244: 8.34		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		708394 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		MCM4_HUMAN (2-885): 0: 847: 28.42
+	Hs
		832607 TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		627208 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		MCM3_HUMAN (186-897): 0: 725: 29.20
+	Hs
		708834 MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		1055658 SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53		MCM6_HUMAN (186-817): 0: 710: 31.18