HitPredict

Interactor 1: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Interactor 2: K1C17 (Q04695)
Keratin, type I cytoskeletal 17 (39.1) (Cytokeratin-17) (CK-17) (Keratin-17) (K17)
Gene: KRT17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0030307 - positive regulation of cell growth
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 304 Hs			1 432
+	Hs
		445015 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C16_HUMAN (80-410): 1.7e-159: 460: 79.28
+	Hs
		359313 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C14_HUMAN (82-430): 1.15e-151: 440: 82.40
+	Hs
		444334 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C19_HUMAN (77-394): 1.39e-146: 424: 73.59
+	Hs
		580001 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C15_HUMAN (83-426): 2.02e-141: 413: 68.66
+	Hs
		802710 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C12_HUMAN (78-426): 1.31e-127: 379: 60.81
+	Hs
		444399 DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35		K1C19_HUMAN (77-394): 1.39e-146: 424: 73.59
+	Hs
		531331 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C10_HUMAN (79-389): 1.15e-123: 372: 69.75
+	Hs
		802611 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K1C24_HUMAN (79-391): 4.21e-114: 346: 62.26
+	Hs
		275168 GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17		K1C13_HUMAN (73-398): 8.48e-143: 417: 70.73
+	Hs
		359329 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K1C14_HUMAN (82-430): 1.15e-151: 440: 82.40
+	Hs
		280492 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KT33A_HUMAN (30-405): 1.98e-141: 411: 52.39
+	Hs
		802647 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C73_HUMAN (4-398): 3.6e-88: 279: 25.68
+	Hs
		802619 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C79_HUMAN (9-406): 3.64e-81: 261: 22.89
+	Hs
		380448 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C6B_HUMAN (50-414): 2.7e-73: 241: 23.43
+	Hs
		531539 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C5_HUMAN (50-398): 1.34e-72: 240: 25.07
+	Hs
		359471 CRK_HUMAN (1-304): 7.82e-68: 215: 100.00		K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71
+	Hs
		280559 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT34_HUMAN (77-395): 9.16e-117: 348: 58.62
+	Hs
		213936 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT86_HUMAN (21-397): 6.62e-90: 282: 26.46
+	Hs
		280786 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		KRT36_HUMAN (2-395): 8.29e-81: 258: 55.72
+	Hs
		359480 GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67		K2C6A_HUMAN (50-414): 3.75e-72: 238: 23.71