HitPredict

Interactor 1: BAG6 (P46379)
Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe)
Gene: BAG6

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0010498 - proteasomal protein catabolic process GO:0031647 - regulation of protein stability
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1132 Hs			1 399
+	Hs
		803807 BAG6_HUMAN (1-1132): 0: 597: 100.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		803794 BAG6_HUMAN (1-1132): 0: 597: 100.00		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		803767 BAG6_HUMAN (1-1132): 0: 597: 100.00		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		803425 BAG6_HUMAN (1-1132): 0: 597: 100.00		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		1136657 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		DDI2_HUMAN (1-399): 1.67e-162: 463: 100.00
+	Hs
		867142 SC24C_HUMAN (380-696): 1.27e-39: 162: 24.18		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Hs
		1355403 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		1355395 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		UBQL2_HUMAN (5-241): 1.08e-47: 173: 15.20
+	Mm
		1246842 UBQL1_MOUSE (5-549): 1.92e-28: 124: 12.41		UBQL2_MOUSE (5-241): 8.2e-42: 157: 15.71
+	Hs
		1345046 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		1345037 UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Mm
		1307911 UBQL4_MOUSE (6-551): 1.5e-26: 118: 13.47		UBQL2_MOUSE (5-241): 8.2e-42: 157: 15.71
+	Dm
		1362833 Q9VWD9_DROME (9-531): 2.99e-29: 125: 13.66		Q9VCD5_DROME (5-227): 2.18e-35: 133: 12.88
+	Sc
		819477 DSK2_YEAST (16-332): 1.34e-26: 115: 20.06		DSK2_YEAST (19-213): 6.83e-31: 123: 15.49
+	Hs
		872226 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		872222 UBQL4_HUMAN (6-549): 7.75e-26: 115: 11.19		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Sc
		697098 DSK2_YEAST (16-332): 1.34e-26: 115: 20.06		RAD23_YEAST (5-202): 3.88e-26: 110: 16.00
+	Hs
		924208 UBQL2_HUMAN (13-587): 2.27e-26: 117: 14.71		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06