HitPredict

Interactor 1: GPN1 (P46577)
GPN-loop GTPase 1 (EC 3.6.5.-) (Gro-1 operon protein 2) (XPA-binding protein 1 homolog)
Gene: gop-2

Interactor 2: Q9XW68 (Q9XW68)
GPN-loop GTPase 3
Gene: gex-4

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.785

Property	Details
Experiments	14704431, 11731503
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ATP_bind_1~ATP_bind_1
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 355 Ce			1 272
+	Ce
		136322 GPN1_CAEEL (1-355): 7.31e-169: 476: 100.00		O01426_CAEEL (3-253): 2.81e-103: 303: 35.97
+	Hs
		1336406 GPN1_HUMAN (22-343): 8.49e-136: 393: 52.80		GPN3_HUMAN (2-267): 1.73e-127: 365: 52.43
+	Hs
		1334507 GPN1_HUMAN (22-343): 8.49e-136: 393: 52.80		GPN2_HUMAN (3-252): 6.5e-120: 346: 40.55
+	Sc
		812021 GPN1_YEAST (32-353): 5.8e-143: 411: 49.85		GPN3_YEAST (2-269): 3.29e-113: 328: 41.91
+	Sc
		812026 GPN1_YEAST (32-353): 5.8e-143: 411: 49.85		GPN2_YEAST (1-252): 2.75e-105: 311: 34.22
+	Sc
		811996 GPN1_YEAST (32-353): 5.8e-143: 411: 49.85		GPN1_YEAST (6-267): 3.4e-94: 284: 24.82
+	Dm
		1359121 Q9V3R3_DROME (1-292): 2.02e-119: 351: 50.00		Q9VI70_DROME (1-269): 2.98e-117: 339: 47.70
+	At
		1122850 QQT2_ARATH (1-349): 1.66e-126: 369: 43.94		QQT1_ARATH (1-252): 1.46e-106: 312: 36.82
+	Dm
		1359123 Q9V3R3_DROME (1-292): 2.02e-119: 351: 50.00		Q9VU67_DROME (2-252): 1.07e-101: 300: 37.45
+	Sc
		987754 GPN3_YEAST (30-289): 9.71e-103: 305: 23.79		GPN2_YEAST (1-252): 2.75e-105: 311: 34.22