Protein: R144A
E3 ubiquitin-protein ligase RNF144A (EC 2.3.2.31) (RING finger protein 144A) (UbcM4-interacting protein 4) (Ubiquitin-conjugating enzyme 7-interacting protein 4)

Gene: R144A, RNF144A
Organism: Homo sapiens
Interactions: 93
UniProt ID: P50876

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0002221 - pattern recognition receptor signaling pathway
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

898221

UB2L3
Ubiquitin-conjugating enzyme E2 L3

6

20

Small-scale

0.947

High

898208

R144A
E3 ubiquitin-protein ligase RNF144A

3

12

Small-scale

0.865

High

168513

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

2

20

Small-scale

0.791

High

898216

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

898229

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

High-throughput

0.698

High

898235

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

20

High-throughput

0.698

High

898215

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

20

High-throughput

0.691

High

507690

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

17

Small-scale

0.647

High

898209

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.647

High

898218

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

20

Small-scale

0.647

High

898257

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

20

Small-scale

0.647

High

898225

CKAP4
Cytoskeleton-associated protein 4

3

0

High-throughput

0.629

High

898212

UBE2K
Ubiquitin-conjugating enzyme E2 K

1

20

High-throughput

0.621

High

226731

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

8

High-throughput

0.606

High

898239

MFSD5
Molybdate-anion transporter

2

1

High-throughput

0.606

High

898254

SC22A
Vesicle-trafficking protein SEC22a

2

1

High-throughput

0.606

High

898260

PD1L1
Programmed cell death 1 ligand 1

1

0

Small-scale

0.586

High

325531

YIF1A
Protein YIF1A

2

0

High-throughput

0.580

High

722418

CTR1
High affinity cationic amino acid transporter 1

2

0

High-throughput

0.580

High

898240

PAQR6
Membrane progestin receptor delta

2

0

High-throughput

0.580

High

898243

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.580

High

898252

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

2

0

High-throughput

0.580

High

362985

EGFR
Epidermal growth factor receptor

1

1

Small-scale

0.561

High

487101

PARP1
Poly [ADP-ribose] polymerase 1

1

1

Small-scale

0.561

High

898210

HSP72
Heat shock-related 70 kDa protein 2

1

3

Small-scale

0.561

High

898253

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

8

High-throughput

0.553

High

75507

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

898258

CLTR2
Cysteinyl leukotriene receptor 2

1

0

High-throughput

0.518

High

898230

ULA1
NEDD8-activating enzyme E1 regulatory subunit

1

0

High-throughput

0.513

High

898255

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.513

High

384127

CO1A1
Collagen alpha-1(I) chain

1

1

High-throughput

0.489

High

465952

CO1A2
Collagen alpha-2(I) chain

1

1

High-throughput

0.489

High

143412

E2F3
Transcription factor E2F3

1

3

Small-scale

0.481

High

898223

E2F1
Transcription factor E2F1

1

3

Small-scale

0.481

High

898236

E2F4
Transcription factor E2F4

1

3

Small-scale

0.481

High

898248

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

7

High-throughput

0.481

High

898264

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

7

High-throughput

0.481

High

168654

CSKP
Peripheral plasma membrane protein CASK

1

5

Small-scale

0.479

High

254088

CTND1
Catenin delta-1

1

4

Small-scale

0.479

High

565824

EF2
Elongation factor 2

1

2

Small-scale

0.479

High

573389

ENPL
Endoplasmin

1

4

Small-scale

0.479

High

615679

RL17
Large ribosomal subunit protein uL22

1

1

Small-scale

0.479

High

675422

TYY1
Transcriptional repressor protein YY1

1

12

Small-scale

0.479

High

699653

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

Small-scale

0.479

High

765262

BMI1
Polycomb complex protein BMI-1

1

2

Small-scale

0.479

High

834159

CSK
Tyrosine-protein kinase CSK

1

2

Small-scale

0.479

High

898211

XPO2
Exportin-2

1

2

Small-scale

0.479

High

898214

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

1

Small-scale

0.479

High

898219

RL10A
Large ribosomal subunit protein uL1

1

1

Small-scale

0.479

High

898224

PRDX1
Peroxiredoxin-1

1

2

Small-scale

0.479

High

898226

DLG1
Disks large homolog 1

1

5

Small-scale

0.479

High

898227

DDX10
Probable ATP-dependent RNA helicase DDX10

1

7

Small-scale

0.479

High

898231

SCRIB
Protein scribble homolog

1

1

Small-scale

0.479

High

898234

RAB35
Ras-related protein Rab-35

1

2

Small-scale

0.479

High

898238

CYTSB
Cytospin-B

1

1

Small-scale

0.479

High

898241

CD109
CD109 antigen

1

1

Small-scale

0.479

High

898242

LN28B
Protein lin-28 homolog B

1

4

Small-scale

0.479

High

898245

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

Small-scale

0.479

High

898246

ZDH23
Palmitoyltransferase ZDHHC23

1

1

Small-scale

0.479

High

898247

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

2

Small-scale

0.479

High

898250

MY18A
Unconventional myosin-XVIIIa

1

3

Small-scale

0.479

High

898251

GCN1
Stalled ribosome sensor GCN1

1

4

Small-scale

0.479

High

898256

MYO5C
Unconventional myosin-Vc

1

2

Small-scale

0.479

High

898261

CALL5
Calmodulin-like protein 5

1

3

Small-scale

0.479

High

898263

XPO7
Exportin-7

1

5

High-throughput

0.479

High

898266

RAP2C
Ras-related protein Rap-2c

1

2

Small-scale

0.479

High

292433

PALM
Paralemmin-1

1

0

Small-scale

0.458

High

336378

SVIL
Supervillin

1

0

Small-scale

0.458

High

460470

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

0

Small-scale

0.458

High

701117

PSB5
Proteasome subunit beta type-5

1

0

Small-scale

0.458

High

710125

EPHA2
Ephrin type-A receptor 2

1

0

Small-scale

0.458

High

774037

ADDA
Alpha-adducin

1

0

Small-scale

0.458

High

837459

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

Small-scale

0.458

High

860091

RS9
Small ribosomal subunit protein uS4

1

0

Small-scale

0.458

High

898228

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

Small-scale

0.458

High

898233

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

Small-scale

0.458

High

898259

ZDH18
Palmitoyltransferase ZDHHC18

1

0

Small-scale

0.458

High

898262

SYLC
Leucine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.458

High

898265

E41L3
Band 4.1-like protein 3

1

0

Small-scale

0.458

High

898232

E2F2
Transcription factor E2F2

1

3

Small-scale

0.439

High

898237

TMM31
Transmembrane protein 31

1

1

High-throughput

0.439

High

136338

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

8

Small-scale

0.437

High

451352

NFM
Neurofilament medium polypeptide

1

5

Small-scale

0.437

High

573937

MYL6B
Myosin light chain 6B

1

2

Small-scale

0.437

High

655116

SFPQ
Splicing factor, proline- and glutamine-rich

1

4

Small-scale

0.437

High

898217

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

Small-scale

0.437

High

898244

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

1

Small-scale

0.437

High

898222

PRKDC
DNA-dependent protein kinase catalytic subunit

4

0

Small-scale

0.363

High

898213

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.279

Low

131365

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

Small-scale

0.249

Low

898220

TPM4
Tropomyosin alpha-4 chain

1

0

Small-scale

0.249

Low

898249

TF3C2
General transcription factor 3C polypeptide 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025