HitPredict

Interactor 1: SSF1 (P38789)
Ribosome biogenesis protein SSF1
Gene: SSF1

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	37968396, 11864607
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Brix~Brix
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 453 Sc			1 291
+	Sc
		1062793 SSF2_YEAST (1-453): 0: 538: 94.04		BRX1_YEAST (1-291): 1.12e-99: 295: 100.00
+	Sc
		782325 SSF1_YEAST (1-453): 0: 544: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		782488 SSF2_YEAST (1-453): 0: 538: 94.04		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		804608 SSF1_YEAST (1-453): 0: 544: 100.00		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Sc
		805112 SSF2_YEAST (1-453): 0: 538: 94.04		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Hs
		1351478 SSF1_HUMAN (2-453): 3.51e-142: 417: 32.33		BRX1_HUMAN (26-286): 1.93e-85: 261: 47.91
+	Sc
		804607 SSF1_YEAST (1-453): 0: 544: 100.00		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		804687 SSF1_YEAST (1-453): 0: 544: 100.00		SSF2_YEAST (10-197): 8.36e-33: 127: 15.17
+	Dm
		1471506 PPAN_DROME (3-423): 2.52e-120: 360: 32.47		BRX1_DROME (8-291): 5.4e-82: 253: 40.91
+	Hs
		1446760 SSF1_HUMAN (2-453): 3.51e-142: 417: 32.33		SSF1_HUMAN (12-281): 5.7e-45: 160: 12.87
+	Dm
		1471496 PPAN_DROME (3-423): 2.52e-120: 360: 32.47		RPF1_DROME (12-252): 5.75e-53: 179: 17.07