HitPredict

Interactor 1: NEDD4 (P46935)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: GRB10 (Q60760)
Growth factor receptor-bound protein 10 (GRB10 adapter protein) (Maternally expressed gene 1 protein)
Gene: GRB10

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.843

The method score is based on:

Property Details
Experiments 10446181, 20980250
Identification Methods two hybrid, affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C2~SH2
Common GO terms GO:0005829 - cytosol
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 887
Mm

1 621
+ Rn
+ Hs
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+ Hs
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+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024