Protein: VTC3
Vacuolar transporter chaperone 3 complex subunit 3 (Phosphate metabolism protein 2) (SPX-dependent polyphosphate polymerase VTC subunit 3) (Vacuolar membrane polyphosphate polymerase accessory subunit 3) (PolyP polymerase)

Gene: VTC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: Q02725

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0000421 - autophagosome membrane
GO:0000822 - inositol hexakisphosphate binding
GO:0005516 - calmodulin binding
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864896

VTC4
Vacuolar transporter chaperone complex subunit 4

5

15

Small-scale

0.912

High

817481

VTC1
Vacuolar transporter chaperone complex subunit 1

4

15

Small-scale

0.890

High

849970

VTC2
Vacuolar transporter chaperone complex subunit 2

1

15

High-throughput

0.618

High

1038135

VTC3
Vacuolar transporter chaperone 3 complex subunit 3

1

15

High-throughput

0.618

High

808356

VTC5
Vacuole transporter chaperone complex subunit 5

2

4

Small-scale

0.584

High

524905

HSP71
Heat shock protein SSA1

2

9

High-throughput

0.571

High

527481

HSP72
Heat shock protein SSA2

2

9

High-throughput

0.571

High

545974

SSB1
Ribosome-associated molecular chaperone SSB1

2

12

High-throughput

0.571

High

449171

CALM
Calmodulin

1

2

Small-scale

0.561

High

919626

TNA1
High-affinity nicotinic acid transporter

1

2

High-throughput

0.541

High

819571

SSB2
Ribosome-associated molecular chaperone SSB2

2

12

High-throughput

0.504

High

547068

PPB
Repressible alkaline phosphatase

1

5

High-throughput

0.479

High

575735

BPT1
Bile pigment transporter 1

1

17

High-throughput

0.479

High

592450

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.479

High

603534

VATA
V-type proton ATPase catalytic subunit A

1

9

High-throughput

0.479

High

628278

ZRC1
Vacuolar zinc transporter ZRC1

1

9

High-throughput

0.479

High

645853

VATE
V-type proton ATPase subunit E

1

5

High-throughput

0.479

High

672709

BPH1
Beige protein homolog 1

1

2

High-throughput

0.479

High

673309

ADP1
Probable ATP-dependent permease

1

7

High-throughput

0.479

High

679991

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

693203

PHO91
Low-affinity phosphate transporter PHO91

1

10

High-throughput

0.479

High

726588

VATC
V-type proton ATPase subunit C

1

1

High-throughput

0.479

High

735750

VA0D
V-type proton ATPase subunit d

1

5

High-throughput

0.479

High

736200

YBT1
ATP-dependent bile acid permease

1

17

High-throughput

0.479

High

740089

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

7

High-throughput

0.479

High

743475

SEC17
Alpha-soluble NSF attachment protein

1

2

High-throughput

0.479

High

743715

VATD
V-type proton ATPase subunit D

1

5

High-throughput

0.479

High

745221

COT1
Vacuolar zinc transporter COT1

1

9

High-throughput

0.479

High

746015

VATL2
V-type proton ATPase subunit c'

1

5

High-throughput

0.479

High

780792

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

4

High-throughput

0.479

High

796502

PFF1
Vacuolar membrane protease

1

5

High-throughput

0.479

High

797031

PHO88
SRP-independent targeting protein 3

1

2

High-throughput

0.479

High

811635

YCFI
Metal resistance protein YCF1

1

17

High-throughput

0.479

High

811670

VATF
V-type proton ATPase subunit F

1

4

High-throughput

0.479

High

815872

KC13
Casein kinase I homolog 3

1

4

High-throughput

0.479

High

815998

VAC8
Vacuolar protein 8

1

4

High-throughput

0.479

High

825949

SYG1
Protein SYG1

1

10

High-throughput

0.479

High

835949

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.479

High

843161

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

10

High-throughput

0.479

High

850719

RMD8
Sporulation protein RMD8

1

11

High-throughput

0.479

High

877885

VATG
V-type proton ATPase subunit G

1

5

High-throughput

0.479

High

919070

VOA1
V0 assembly protein 1

1

3

High-throughput

0.479

High

919136

VSB1
Vacuolar basic amino acid transporter VSB1

1

5

High-throughput

0.479

High

1025011

NUM1
Nuclear migration protein NUM1

1

5

High-throughput

0.479

High

1038137

RMD1
Sporulation protein RMD1

1

11

High-throughput

0.479

High

1038141

SMF3
Iron transporter SMF3

1

3

High-throughput

0.479

High

1038142

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

4

High-throughput

0.479

High

1038143

NYV1
Vacuolar v-SNARE NYV1

1

6

High-throughput

0.479

High

1038144

YVC1
Calcium channel YVC1

1

5

High-throughput

0.479

High

1038146

YPK9
Vacuolar cation-transporting ATPase YPK9

1

5

High-throughput

0.479

High

1038148

VCX1
Vacuolar calcium ion transporter

1

10

High-throughput

0.479

High

438761

SC160
Protein SCP160

1

0

High-throughput

0.458

High

1038147

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

865526

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.457

High

1038139

PIN3
[PSI+] inducibility protein 3

1

4

High-throughput

0.457

High

1035040

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.457

High

365161

KPYK1
Pyruvate kinase 1

1

3

High-throughput

0.437

High

439405

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.437

High

444604

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.437

High

579930

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.437

High

647192

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.437

High

707958

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.437

High

727263

HS104
Heat shock protein 104

1

4

High-throughput

0.437

High

779323

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

795165

NU170
Nucleoporin NUP170

1

5

High-throughput

0.437

High

812109

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

812589

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

824935

TM108
Protein TMA108

1

2

High-throughput

0.437

High

881421

TOM22
Mitochondrial import receptor subunit TOM22

1

2

High-throughput

0.437

High

963663

H3
Histone H3

1

5

High-throughput

0.437

High

1038136

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.437

High

1038140

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.437

High

1038145

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.437

High

776386

YET1
Endoplasmic reticulum transmembrane protein 1

1

0

High-throughput

0.426

High

393203

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.407

High

804072

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.265

Low

368037

ENO2
Enolase 2

1

0

High-throughput

0.249

Low

1038138

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

812256

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low

816738

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

865046

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025