HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 31501420
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0030054 - cell junction
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 2472
+	Hs
		1045530 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		1045510 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		164579 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SPTN2_HUMAN (141-1932): 1.25e-65: 250: 20.41
+	Hs
		963426 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		808520 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		808624 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Hs
		521619 SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		521493 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Dm
		1182589 KIBRA_DROME (169-320): 3.18e-32: 133: 28.29		Q7KV70_DROME (1-592): 1.99e-24: 115: 29.61
+	Hs
		521598 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211645 MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		1350503 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		828634 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		CENPF_HUMAN (1723-2444): 8.12e-13: 77: 9.28