HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	31393050, 24366813, 37005481
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 303
+	Hs
		808928 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		183079 YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		1349034 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Dm
		1366964 Q9W325_DROME (254-504): 3.56e-53: 187: 11.42		Q9VH81_DROME (4-246): 6.54e-32: 125: 16.87
+	Hs
		183158 WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02
+	Hs
		858677 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		1078503 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		TOM34_HUMAN (26-117): 9.37e-11: 63.5: 35.87