HitPredict

Interactor 1: LSM1 (P47017)
Sm-like protein LSm1 (SPB8 protein)
Gene: LSM1

Interactor 2: LSM3 (P57743)
U6 snRNA-associated Sm-like protein LSm3 (SmX4 protein)
Gene: LSM3

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.983

Property	Details
Experiments	10747033, 10900456, 10428970, 11805826, 16554755, 19740761, 37968396, 14759368, 17513695, 18719252, 18719247, 19111170, 20108977, 22450758, 16429126
Identification Methods	biochemical, affinity chromatography technology, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005634 - nucleus GO:0005737 - cytoplasm GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Sc			1 89
+	Sc
		810514 LSM1_YEAST (1-172): 4.98e-64: 196: 100.00		LSM1_YEAST (8-84): 1.39e-21: 84.5: 29.87
+	Sc
		810527 LSM1_YEAST (1-172): 4.98e-64: 196: 100.00		LSM7_YEAST (2-83): 1.07e-20: 80.6: 30.23
+	Sc
		768230 LSM1_YEAST (1-172): 4.98e-64: 196: 100.00		LSM5_YEAST (4-83): 2.79e-19: 76.4: 24.69
+	At
		1228013 LSM1B_ARATH (28-162): 5.17e-37: 125: 32.59		LSM7_ARATH (2-86): 2.33e-25: 92.2: 34.88
+	Hs
		167663 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		RSMB_HUMAN (10-86): 3.53e-24: 92.9: 26.51
+	Hs
		167725 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM7_HUMAN (2-85): 7.35e-25: 91: 30.59
+	Hs
		167680 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM3_HUMAN (1-81): 7.88e-25: 90.6: 40.23
+	Mm
		912216 LSM1_MOUSE (38-164): 3.13e-33: 116: 37.01		LSM3_MOUSE (1-81): 7.88e-25: 90.6: 40.23
+	Dm
		1213200 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		Q8IMX8_DROME (1-81): 2.66e-25: 91.8: 43.68
+	Hs
		167727 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM5_HUMAN (4-85): 3.22e-21: 81.4: 23.17
+	Sp
		251599 LSM7_SCHPO (11-120): 3.83e-29: 105: 23.21		LSM7_SCHPO (2-85): 1.17e-25: 93.3: 29.76
+	Hs
		167681 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		LSM6_HUMAN (2-81): 5.33e-21: 80.2: 28.75
+	Hs
		167683 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		SMD2_HUMAN (4-76): 1.47e-20: 80.2: 28.05
+	Hs
		321370 LSM8_HUMAN (43-135): 8.57e-29: 104: 32.98		RSMB_HUMAN (10-86): 3.53e-24: 92.9: 26.51
+	Dm
		1368680 Q9W2K2_DROME (36-165): 9.12e-32: 112: 40.00		Q9VJI7_DROME (2-86): 6.81e-22: 83.7: 28.74
+	Hs
		167679 LSM1_HUMAN (38-164): 1.07e-33: 117: 36.22		RUXG_HUMAN (8-81): 2.24e-20: 78.7: 27.03
+	Dm
		1373283 Q9W2K2_DROME (36-165): 9.12e-32: 112: 40.00		Q9VRT7_DROME (4-84): 8.53e-22: 82.6: 22.22
+	Mm
		912214 LSM8_MOUSE (43-135): 8.57e-29: 104: 32.98		LSM3_MOUSE (1-81): 7.88e-25: 90.6: 40.23
+	Dm
		1368679 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		Q9VJI7_DROME (2-86): 6.81e-22: 83.7: 28.74
+	Dm
		1367660 Q9W087_DROME (44-136): 1.83e-30: 108: 26.60		SMD2_DROME (4-76): 1.61e-20: 80.2: 30.49