HitPredict

Interactor 1: NU192 (P47054)
Nucleoporin NUP192 (Nuclear pore protein NUP192)
Gene: NUP192

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	26344569, 35679425, 18046405, 27194810
Identification Methods	pull down, affinity chromatography technology, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore GO:0017056 - structural constituent of nuclear pore GO:0046822 - regulation of nucleocytoplasmic transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1683 Sc			1 1317
+	Sc
		811041 NU192_YEAST (1-1683): 0: 1682: 100.00		NU100_YEAST (45-542): 1.84e-14: 80.8: 14.10
+	Sc
		541892 NU192_YEAST (1-1683): 0: 1682: 100.00		NSP1_YEAST (3-459): 5.33e-11: 69.3: 13.35
+	Sc
		811031 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP57_YEAST (118-368): 1.26e-10: 67.7: 15.33
+	Sc
		811042 NU192_YEAST (1-1683): 0: 1682: 100.00		NU116_YEAST (43-484): 6.18e-10: 66.2: 12.29
+	Sc
		811039 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP49_YEAST (3-140): 3.57e-10: 66.1: 29.68
+	Sc
		811032 NU192_YEAST (1-1683): 0: 1682: 100.00		NUP42_YEAST (2-285): 1.65e-09: 63.8: 17.86
+	Sc
		774354 NU192_YEAST (1-1683): 0: 1682: 100.00		NU159_YEAST (2-479): 6.29e-09: 62.7: 11.43
+	Hs
		858020 NU205_HUMAN (23-1642): 0: 1308: 15.72		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Hs
		834649 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727298 NU205_HUMAN (23-1642): 0: 1308: 15.72		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43
+	Xl
		1125563 Q642R6_XENLA (24-1642): 0: 1216: 15.16		Q5EWX9_XENLA (1-330): 2.1e-13: 77.3: 16.09
+	Xl
		1145147 Q642R6_XENLA (24-1642): 0: 1216: 15.16		Q91349_XENLA (166-464): 1.42e-09: 64.3: 12.54
+	Tt
		101880 NU192_CHATD (24-1644): 0: 1131: 20.07		NUP49_CHATD (136-400): 3.34e-13: 75.8: 16.85
+	Tt
		101882 NU192_CHATD (24-1644): 0: 1131: 20.07		NU145_CHATD (7-472): 2.07e-10: 67.8: 12.30
+	Hs
		857991 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Hs
		834612 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727269 NU188_HUMAN (633-1341): 1.14e-87: 320: 13.16		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43