HitPredict

Interactor 1: VTC4 (P47075)
Vacuolar transporter chaperone complex subunit 4 (Phosphate metabolism protein 3) (Polyphosphate kinase) (SPX-dependent polyphosphate polymerase VTC subunit 4) (Vacuolar membrane polyphosphate polymerase catalytic subunit) (PolyP polymerase) (EC 2.7.4.1)
Gene: VTC4

Interactor 2: VTC3 (Q02725)
Vacuolar transporter chaperone 3 complex subunit 3 (Phosphate metabolism protein 2) (SPX-dependent polyphosphate polymerase VTC subunit 3) (Vacuolar membrane polyphosphate polymerase accessory subunit 3) (PolyP polymerase)
Gene: VTC3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 25315834, 37066886, 37968396, 27587415, 37156835
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains VTC~VTC
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0000421 - autophagosome membrane
GO:0000822 - inositol hexakisphosphate binding
GO:0005516 - calmodulin binding
GO:0005783 - endoplasmic reticulum
and 11 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 721
Sc

1 835
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024