Protein: GRIA1
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)

Gene: GRIA1
Organism: Homo sapiens
Interactions: 49
UniProt ID: P42261

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001919 - regulation of receptor recycling
GO:0001965 - G-protein alpha-subunit binding
GO:0004971 - AMPA glutamate receptor activity
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838442

GRIA2
Glutamate receptor 2

4

18

Small-scale

0.873

High

838476

CCG2
Voltage-dependent calcium channel gamma-2 subunit

2

15

Small-scale

0.768

High

838451

DLG1
Disks large homolog 1

4

20

Small-scale

0.703

High

838470

GRID1
Glutamate receptor ionotropic, delta-1

1

19

High-throughput

0.691

High

838441

GRIA1
Glutamate receptor 1

1

18

Small-scale

0.647

High

668200

CXCR2
C-X-C chemokine receptor type 2

3

7

Small-scale

0.640

High

215875

GRID2
Glutamate receptor ionotropic, delta-2

1

18

Small-scale

0.618

High

838443

GRIA3
Glutamate receptor 3

1

18

Small-scale

0.618

High

838445

GRIA4
Glutamate receptor 4

1

18

Small-scale

0.618

High

838452

GRIK2
Glutamate receptor ionotropic, kainate 2

1

18

Small-scale

0.618

High

838458

CNIH2
Protein cornichon homolog 2

1

3

Small-scale

0.618

High

838462

CCG8
Voltage-dependent calcium channel gamma-8 subunit

1

15

Small-scale

0.618

High

838467

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

14

Small-scale

0.618

High

838473

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

8

Small-scale

0.602

High

838464

E41L1
Band 4.1-like protein 1

2

12

Small-scale

0.595

High

838444

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

1

Small-scale

0.584

High

838465

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

Small-scale

0.561

High

217400

E41L2
Band 4.1-like protein 2

1

12

Small-scale

0.552

High

156244

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

3

High-throughput

0.536

High

838449

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.536

High

838461

UN45B
Protein unc-45 homolog B

1

1

High-throughput

0.536

High

838454

BECN1
Beclin-1

1

1

High-throughput

0.515

High

838455

RB11B
Ras-related protein Rab-11B

1

2

High-throughput

0.515

High

140164

SDCB1
Syntenin-1

1

20

Small-scale

0.501

High

603195

KPCA
Protein kinase C alpha type

1

7

Small-scale

0.501

High

658572

KS6B1
Ribosomal protein S6 kinase beta-1

1

9

Small-scale

0.501

High

838446

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

Small-scale

0.501

High

838453

SQSTM
Sequestosome-1

1

4

Small-scale

0.501

High

838463

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

Small-scale

0.501

High

838466

PICK1
PRKCA-binding protein

1

11

Small-scale

0.501

High

838474

GRIP1
Glutamate receptor-interacting protein 1

1

20

Small-scale

0.501

High

838472

ZN232
Zinc finger protein 232

1

0

High-throughput

0.493

High

240982

PRKN
E3 ubiquitin-protein ligase parkin

1

6

High-throughput

0.479

High

250491

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

1

Small-scale

0.479

High

838447

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.479

High

838448

RB11A
Ras-related protein Rab-11A

1

2

Small-scale

0.479

High

838450

TROP
Trophinin

1

3

High-throughput

0.479

High

838456

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.479

High

838457

RN220
E3 ubiquitin-protein ligase RNF220

1

4

Small-scale

0.479

High

838460

PHLB2
Pleckstrin homology-like domain family B member 2

1

7

Small-scale

0.479

High

838469

ANC2
Anaphase-promoting complex subunit 2

1

1

Small-scale

0.479

High

838475

MYO5A
Unconventional myosin-Va

1

4

Small-scale

0.479

High

487050

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

838471

FZR1
Fizzy-related protein homolog

1

0

Small-scale

0.458

High

605587

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

Small-scale

0.445

High

838459

ASCL4
Achaete-scute homolog 4

1

0

High-throughput

0.268

Low

838468

KLF15
Krueppel-like factor 15

1

0

High-throughput

0.268

Low

60143

TARP
T-cell receptor gamma alternate reading frame protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025