Protein: GRIK2
Glutamate receptor ionotropic, kainate 2 (GluK2) (Excitatory amino acid receptor 4) (EAA4) (Glutamate receptor 6) (GluR-6) (GluR6)

Gene: GRIK2
Organism: Homo sapiens
Interactions: 22
UniProt ID: Q13002

Gene Ontology (top 5):
GO:0000149 - SNARE binding
GO:0001662 - behavioral fear response
GO:0004970 - glutamate-gated receptor activity
GO:0005234 - extracellularly glutamate-gated ion channel activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1092402

GRIK5
Glutamate receptor ionotropic, kainate 5

5

19

Small-scale

0.912

High

1092399

GRIK2
Glutamate receptor ionotropic, kainate 2

3

19

Small-scale

0.830

High

1006057

DLG4
Disks large homolog 4

4

20

Small-scale

0.703

High

811287

GRIK1
Glutamate receptor ionotropic, kainate 1

1

19

Small-scale

0.647

High

1092401

GRIK4
Glutamate receptor ionotropic, kainate 4

1

19

Small-scale

0.647

High

1092404

NETO1
Neuropilin and tolloid-like protein 1

1

5

Small-scale

0.647

High

1092406

PICK1
PRKCA-binding protein

2

11

Small-scale

0.631

High

215877

GRID2
Glutamate receptor ionotropic, delta-2

1

19

Small-scale

0.618

High

838452

GRIA1
Glutamate receptor 1

1

18

Small-scale

0.618

High

838490

GRIA2
Glutamate receptor 2

1

18

Small-scale

0.618

High

1091485

DLG1
Disks large homolog 1

2

20

Small-scale

0.584

High

140244

SDCB1
Syntenin-1

1

20

Small-scale

0.573

High

1092408

GRIP1
Glutamate receptor-interacting protein 1

1

20

Small-scale

0.501

High

1092407

CACO1
Calcium-binding and coiled-coil domain-containing protein 1

1

5

High-throughput

0.494

High

241543

PRKN
E3 ubiquitin-protein ligase parkin

1

6

Small-scale

0.479

High

429806

JUN
Transcription factor Jun

1

1

High-throughput

0.479

High

1092403

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

2

Small-scale

0.479

High

1092405

DLG3
Disks large homolog 3

1

20

Small-scale

0.479

High

218131

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

624501

WT1
Wilms tumor protein

1

1

High-throughput

0.417

High

1092400

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025